Pharmacokinetics of betamethasone in pre‐eclampsia: An in vivo and ex vivo study
Aims To enhance understanding of betamethasone and its metabolites' pharmacokinetics in pregnancy, specifically early‐onset pre‐eclampsia, through a population pharmacokinetic model. Additionally, to investigate the placental metabolism and transfer of betamethasone and its main metabolites.
Sam Schoenmakers+15 more
wiley +1 more source
Breast cancer and the steadily increasing maternal age: are they colliding? [PDF]
Londero AP+4 more
europepmc +1 more source
EudraVigilance insights: Suspected adverse drug reactions in infants through breastfeeding
Aims We aimed to describe suspected adverse drug reactions (ADRs) in infants resulting from medications transmitted through mothers' milk, as reported to the European ADR database, EudraVigilance. The research sought to understand the frequency, seriousness and nature of these ADRs to assess potential risks associated with maternal medication use ...
Ida M. Heerfordt+7 more
wiley +1 more source
Association between interpregnancy interval and adverse perinatal outcomes according to maternal age in the context of China's two-child policy. [PDF]
Xiu S+10 more
europepmc +1 more source
Triple marker screening for fetal chromosomal abnormalities in Korean women of advanced maternal age
Sei Kwang Kim+8 more
openalex +1 more source
Aims Atypical colitis (presenting reverse gradient colitis, backwash ileitis or rectal sparing) is associated with primary sclerosing cholangitis–ulcerative colitis (PSC). Oral vancomycin has been used to manage paediatric atypical colitis with/without confirmed PSC. Different preparations had shown different efficacy.
Laura Räisänen+4 more
wiley +1 more source
Placental trophoblast aging in advanced maternal age is related to increased oxidative damage and decreased YAP. [PDF]
Guo S+6 more
europepmc +1 more source
Prescription drug use in breastfeeding mothers and infant exposure: A register‐based cohort study
Abstract Aims Breast milk is the optimal infant nutrition; however, many infants may be exposed to prescription drugs if used by their mothers during breastfeeding. The aim of this study was to evaluate the prevalence and patterns of prescription drug use among breastfeeding mothers and to assess the availability of relative infant dose information for
Ditte Resendal Gotfredsen+5 more
wiley +1 more source
Maternal age and the rising incidence of hypertensive disorders of pregnancy: A comprehensive analysis of national claims data from Japan. [PDF]
Maeda N+9 more
europepmc +1 more source