Results 321 to 330 of about 9,803,652 (406)

Integrated proteomic and metabolomic analysis elucidates the effects and mechanisms of Qiziyusi decoction on IVF outcomes in advanced maternal age infertility. [PDF]

Front Endocrinol (Lausanne)
Jin Q, Zhao J, Ma Y, Zhang Y, Yan M, Song J, Cao X, Sun Z.   +7 more
europepmc   +1 more source

From Brain Health to Brain Economy

Brain Health, EarlyView.
Yongjun Wang
wiley   +1 more source

A Phase 1, Randomized, Placebo‐Controlled, Multiple‐Dose, Double‐Blind Study to Evaluate and Compare the Pharmacokinetics and Safety of Rimegepant in Healthy Adult Japanese and Caucasian Individuals

Clinical Pharmacology in Drug Development, EarlyView.
Abstract This Phase 1, randomized, placebo‐controlled, double‐blind study assessed the pharmacokinetic profile of rimegepant (25, 75, or 150 mg once daily for 14 days) in healthy Japanese and Caucasian adults. Exposures were modestly increased in Japanese participants compared with Caucasian participants following a single dose of rimegepant (Day 1 ...
Rajinder Bhardwaj, Chay Ngee Lim, Yinhua Li, Kyle T. Matschke, Richard Bertz, Robert Croop, Jing Liu   +6 more
wiley   +1 more source

Pediatric Developmental Safety Assessment: Are We Ready for the Next Thalidomide?

Clinical Pharmacology &Therapeutics, EarlyView.
Pediatric drug development has achieved remarkable success in the last 20 years with over 1,000 products studied in pediatric patients. This success has been driven in part by an increased understanding of pediatric disease processes. The aspect that has been largely overlooked is the potential adverse effect of new drugs on pediatric developmental ...
Gilbert J. Burckart, Susan M. Abdel‐Rahman, Gelareh Abulwerdi, Sherbet Samuels, Rebecca Racz, Mohamed A. Mohamoud, Nicholas P. Tatonetti   +6 more
wiley   +1 more source

Positive association between fibrinogen-to-albumin ratio and preeclampsia risk in pregnant women of advanced maternal age: implications for clinical risk assessment. [PDF]

Front Cardiovasc Med
Wang N, Liu S, Duan X, Xie H, Ge L, Huang S.   +5 more
europepmc   +1 more source

PharmVar GeneFocus: NAT2—Genetic Variation and Updated Nomenclature

Clinical Pharmacology &Therapeutics, EarlyView.
The Pharmacogene Variation Consortium (PharmVar) provides nomenclature for the highly polymorphic human N‐acetyltransferase 2 (NAT2) gene. NAT2 metabolizes several clinically used drugs including isoniazid, hydralazine, amifampridine, procainamide, and sulfonamides such as dapsone, and also some highly carcinogenic arylamines.
Georgia Papanikolaou, Estella S. Poloni, José A.G. Agúndez, Raquel L.F. Teixeira, Erin C. Boone, Adalberto Rezende Santos, Michelle Whirl‐Carrillo, Katrin Sangkuhl, Teri E. Klein, Mariam R. Habil, Giannoulis Fakis, Rodney F. Minchin, David W. Hein, Sotiria Boukouvala, Andrea Gaedigk   +14 more
wiley   +1 more source

Research Progress and Clinical Implications of Generative Artificial Intelligence in Perinatal Health Care for Advanced Maternal Age Pregnant Women [Retraction]. [PDF]

Int J Womens Health
europepmc   +1 more source

Investigating the association between maternal age and cerebral palsy incidence: A meta-analysis. [PDF]

Medicine (Baltimore)
Lee JM, Pak K.
europepmc   +1 more source

The influence of advanced maternal age on the success rate, delivery mode and maternal and fetal outcomes of pregnant women undergoing external cephalic version: a retrospective cohort study. [PDF]

BMC Pregnancy Childbirth
Xiang Y, Lin H, Zhou Q, Tang M, Chen R, Zeng D, Ou Y, Zheng S, Luo H, Mo W, Zhu Y, Huang S, Li Z.   +12 more
europepmc   +1 more source