Results 211 to 220 of about 793,157 (300)

Tacrolimus exposure during pregnancy in kidney and liver transplantation recipients: A comparison between whole blood and plasma concentration‐to‐dose ratios

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Tacrolimus monitoring is generally performed in whole blood (WB). Most (>85%) of circulating tacrolimus is bound to red blood cells. During pregnancy, WB monitoring might be suboptimal because of physiological changes including increased plasma volume and decreased haematocrit.
Jildau R. Meinderts, Paola Mian, Frederike G. I. van Vilsteren, Karien M. H. van de Wetering, Jelmer R. Prins, Stefan P. Berger, Daan J. Touw, Margriet F. C. de Jong   +7 more
wiley   +1 more source

Microbial dysbiosis and associated disease mechanisms in maternal and child health. [PDF]

Infect Immun
Ahmed U, Fatima F, Farooq HA.
europepmc   +1 more source

Developing medication independence: The experience of UK teenagers

British Journal of Clinical Pharmacology, EarlyView.
Aims There is a progression through childhood from being provided medications by caregivers to having to take responsibility for medications yourself, but little is known about when the transition of adolescents managing medicines begins. The aim of this study was to obtain a cross‐sectional sample of UK adolescents and when they become independent ...
Holly Hutchins, Charlotte King, Louis Bioletti, Tsegay Gebru, Alder Hey Research Ambassadors, Daniel B. Hawcutt   +5 more
wiley   +1 more source

Distribution and antimicrobial resistance profiles of common blood culture isolates in a maternal and child health specialty hospital, Shenzhen (January 2021-October 2025), China. [PDF]

Front Microbiol
Ding T, Lin S, Yang K, Zhou X, Liu S, Liu X, Zhang Q, Zhou Z.   +7 more
europepmc   +1 more source

Use of antiemetics in early pregnancy 2012–2022: A cross‐sectional study

British Journal of Clinical Pharmacology, EarlyView.
Aim Nausea and vomiting in pregnancy impact quality of life, yet many pregnant women feel dismissed by healthcare professionals, despite the safety of first‐line antiemetic treatments for both mother and fetus. Therefore, this study aims to describe the prevalence of patient‐reported antiemetic use in early pregnancy in Copenhagen, Denmark, the changes
Katrine Bak Wraae, Nanna Roed Ballegaard, Mie Lærkeholm Hede, Line Buchgreitz, Ane Lilleøre Rom, Hanne Kristine Hegaard, Nina Olsén Nathan   +6 more
wiley   +1 more source

Leveraging geospatial technology for effective health planning for maternal and child health in Nigeria. [PDF]

Oxf Open Digit Health
Dorayi AA, Bello SA, Yaro HS, Usman H, Ibitoye O, Agbe P, Afape A, Hildi AU, Futrell L, Abdulkarim M, Levy M, Snell J, Borkovska O, Maidoki N, Tafoki F, Akinsomi F, Adekanmbi O, Anebelundu C.   +17 more
europepmc   +1 more source

A phase 1 evaluation of inhaled oxytocin: Physiologically‐based pharmacokinetic model informed dosing of a novel heat‐stable oxytocin delivery system

British Journal of Clinical Pharmacology, EarlyView.
Aim To develop and validate a physiologically‐based pharmacokinetic (PBPK) model enabling inhaled oxytocin dose selection for clinical evaluation. Subsequently, to conduct a phase 1 study investigating the pharmacokinetics and safety of selected doses of an optimized inhaled oxytocin product in healthy, non‐pregnant female participants.
Pete Lambert, Carl M. J. Kirkpatrick, Rory Marriott, Siladitya Ray Chaudhuri, David Polidori, Bart Remmerie, Michelle P. McIntosh   +6 more
wiley   +1 more source

From handbooks to platforms: Japan's maternal and child health services in the digital era. [PDF]

J Glob Health
Imoto N, Hayashi M.
europepmc   +1 more source

Paternal use of metformin and risk of major congenital malformations: A meta‐analysis of 4 studies

British Journal of Clinical Pharmacology, EarlyView.
Abstract Metformin is the first‐line drug for the treatment of Type 2 diabetes. In 2022, a Danish registry‐based study reported a 40% increased risk of major congenital malformations following paternal exposure during spermatogenesis. This raised widespread concern about the use of metformin in males of reproductive age.
Per Damkier, Marleen M. H. J. van Gelder, Krista F. Huybrechts, Lin‐Chieh Meng, Sonia Hernandez‐Diaz, Jan Nielsen, Bente M. Nørgård, Hedvig Nordeng   +7 more
wiley   +1 more source

Use of modern contraceptive methods among women of childbearing age attending maternal and child health services in Abidjan and Agboville (Cote d'Ivoire). [PDF]

BMC Public Health
Essis EML, Cissé K, Kpebo DOD.
europepmc   +1 more source