Results 111 to 120 of about 578,006 (359)

The role of negative maternal affective states and infant temperament in early interactions between infants with cleft lip and their mothers [PDF]

open access: yes, 2012
OBJECTIVES: The study examined the early interaction between mothers and their infants with cleft lip, assessing the role of maternal affective state and expressiveness and differences in infant temperament.
Borgatti, R.   +6 more
core   +1 more source

Dose‐Dependent Reprogramming of Chromatin Accessibility by SOX4 Drives the Transcriptional Response to Iron Overload

open access: yesAdvanced Science, EarlyView.
This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li   +15 more
wiley   +1 more source

Maternal immune activation and strain specific interactions in the development of autism-like behaviors in mice. [PDF]

open access: yes, 2013
It is becoming increasingly apparent that the causes of autism spectrum disorders (ASD) are due to both genetic and environmental factors. Animal studies provide important translational models for elucidating specific genetic or environmental factors ...
Ashwood, P   +5 more
core   +2 more sources

Metabolic Imbalance Triggers Adaptive Remodeling to Accelerate Diploidization in Murine Haploid Embryonic Stem Cells

open access: yesAdvanced Science, EarlyView.
In this article, Shuai and colleagues demonstrate that metabolic remodeling drives self‐diploidization in murine haploid ESCs (haESCs). Mitochondrial dysfunction and imbalanced pyruvate metabolism underlie this process. Genome‐wide screening using haESCs identifies key mitochondrial quality‐control related genes, enabling a metabolism‐based medium that
Yi Fu   +11 more
wiley   +1 more source

Correlation of maternal and aggressive behaviors in normal and sleep-restricted lactating rats

open access: yesSleep Science, 2013
Objectives: The behavioral phenotype observed during lactation is peculiar, mainly due to the rise of two specific behaviors: maternal aggressive behavior and maternal care.
Gabriel Natan Pires   +2 more
doaj   +1 more source

Maternal Emotion Coaching and Depressive Symptoms and Children's Problem Behaviors [PDF]

open access: yes, 2014
The emotion socialization strategies that mothers use with their children impact children’s adjustment outcomes, such as internalizing and externalizing behavior problems.
Harriger, Danielle
core  

Effects of Maternal Views and Support on Childhood Development Through Joint Play [PDF]

open access: yes, 2019
Background: Playful interactions draw a mother and child toward each other in positive ways; therefore, time spent in playful interactions with a responsive mother may be a developmental asset for a child.
Grinion, Sherraine   +2 more
core   +2 more sources

MEOX1 Coordinates Autocrine‐Paracrine Programs via SPHK1/S1P to Promote Lymph Node Metastasis in Ovarian Cancer

open access: yesAdvanced Science, EarlyView.
In ovarian cancer, MEOX1 activates the SPHK1/S1P pathway to promote both tumor progression and tumor–stroma crosstalk. MEOX1‐dependent signaling drives CAF activation, enhances VEGF‐C expression, and stimulates lymphangiogenesis, ultimately facilitating lymph node metastasis.
Jiajia Li   +10 more
wiley   +1 more source

Gasdermin D‐Mediated Release of IL‐33 Results in Fetal Brain Developmental Abnormalities During Maternal Colitis

open access: yesAdvanced Science, EarlyView.
Under colitis, Gsdmd mediates the release of IL‐33 from the epithelium of pregnant mice. IL‐33 can cross the placenta and enhance the proliferative capacity of neural stem cells, ultimately resulting in behavioral deficits in the offspring. Excessive pyroptosis in the colonic epithelium also triggers the translocation of LPS, which in turn increases ...
Huiyang Jia   +4 more
wiley   +1 more source

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