Results 81 to 90 of about 402,559 (310)

Association between serum albumin and 42-day postpartum mortality in women with acute fatty liver of pregnancy: a retrospective study

open access: yesFrontiers in Medicine
IntroductionAcute Fatty Liver of Pregnancy (AFLP) is a rare, life-threatening complication during pregnancy, characterized by acute liver failure, endangering both mother and fetus. Albumin (ALB), synthesized by the liver, is vital for maintaining plasma
Yuxin Fang   +8 more
doaj   +1 more source

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

open access: yesAdvanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang   +12 more
wiley   +1 more source

Peripartum infections and associated maternal mortality in rural Malawi [PDF]

open access: yes, 2011
Article approval pendingTo assess associations between maternal mortality and severe morbidity and human immunodeficiency virus (HIV) infection, uptake of antiretroviral therapy, obstetric infections, and nonobstetric infections in a rural Malawian ...
Ahmad   +23 more
core   +3 more sources

SLC2A3‐Mediated Lactate Metabolism Promotes Lung Cancer Bone Metastasis by Modulating P53 Lactylation and Immune Evasion

open access: yesAdvanced Science, EarlyView.
SLC2A3 derived lactate promotes metastasis through p53 lactylation at K120 and osteoclast differentiation. Pharmacological inhibition of SLC2A3 upregulates PD‐1 expression on CD8+ T cells via lactate induced p53 lactylation, which modulates immune evasion. ABSTRACT Bone metastasis is a devastating consequence of lung cancer.
Yi Ding   +10 more
wiley   +1 more source

Physical violence during pregnancy: prevalence and outcomes

open access: yesPayesh, 2003
Objective(s): To assess frequency of physical violence during pregnancy by womenchr('39')s husbands and to study its maternal complications and birth outcomes.
Nojoumi M, Akrami Z
doaj  

The diagnostic and therapeutic difficulties in management with pheochromocytoma in pregnancy – a review

open access: yesJournal of Education, Health and Sport, 2019
Introduction: Pheochromocytoma (PCC) is a very rare and life-threatening condition in pregnancy. According to different data, it occurs in about 0,00002%-0,007% of pregnant women. The early diagnosis and the proper clinical management play a crucial role
Michał Litwińczuk   +2 more
doaj   +1 more source

Caspase‐3/GSDME‐Mediated Trophoblast Pyroptosis and Reciprocal Macrophage Polarization Contribute to Inflammation in Early‐Onset Preeclampsia

open access: yesAdvanced Science, EarlyView.
In trophoblast cells, T/S (TNFα + SM164) activated caspase‐3, which cleaved GSDME to switch apoptosis to pyroptosis, causing cell swelling, membrane rupture, and release of LDH, HMGB1, IL‐1β and IL‐18. These cytokines induced pro‐inflammatory macrophage polarization, which in turn reinforced pyroptotic signaling in trophoblasts, amplifying systemic ...
Baoying Huang   +15 more
wiley   +1 more source

Emergency peripartum hysterectomy, physical and mental consequences: a 6-year study [PDF]

open access: yes, 2016
Emergency peripartum hysterectomy (EPH) is performed for massive postpartum hemorrhage following a cesarean delivery or vaginal delivery, in order to save the patient’s life. The current study was performed on a sample of 13.162 patients, which underwent
Bacalbașa, Nicolae   +4 more
core   +4 more sources

cuteHap: Haplotype‐Aware Structural Variant Detection in Phased Long‐Read Sequencing Data

open access: yesAdvanced Science, EarlyView.
cuteHap is a haplotype‐aware structural variant detection method designed for phased long‐read sequencing. By employing self‐adaptive clustering and credibility‐prioritized beam search algorithms, cuteHap generates accurate haplotype‐resolved calls and outperforms state‐of‐the‐art tools.
Shuqi Cao   +7 more
wiley   +1 more source

Issues Regarding the Peruvian Maternal and Child Healthcare System [PDF]

open access: yes, 2008
This paper highlights the deficiencies of the Peruvian Healthcare system. Despite the treaties and covenants the Peruvian government has signed, it has done little to mitigate the ills of its broken healthcare system.
Cassidy, Patrick
core   +1 more source

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