Results 121 to 130 of about 255,957 (299)

A phase 1 evaluation of inhaled oxytocin: Physiologically‐based pharmacokinetic model informed dosing of a novel heat‐stable oxytocin delivery system

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim To develop and validate a physiologically‐based pharmacokinetic (PBPK) model enabling inhaled oxytocin dose selection for clinical evaluation. Subsequently, to conduct a phase 1 study investigating the pharmacokinetics and safety of selected doses of an optimized inhaled oxytocin product in healthy, non‐pregnant female participants.
Pete Lambert   +6 more
wiley   +1 more source

Maternal Mortality Evaluation: A Case Study in Bantul, Yogyakarta

open access: yes, 2019
Background: Maternal mortality rate is one of the indicators to measure the level of a woman's health. The maternal mortality rate in Indonesia is still high, it's about 190/100.000 live birth.
Dewi, Arlina   +2 more
core  

Identification of major congenital malformations based on healthcare databases in France: A proof‐of‐concept study using the epi‐meres nationwide mother–child register

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Besides registries, healthcare databases can provide useful information for assessing the frequency of major congenital malformations (MCMs) and investigating their risk factors, particularly medication exposures. This study aimed to assess the validity of MCMs identification based on French national, comprehensive healthcare databases ...
Tom Duchemin   +7 more
wiley   +1 more source

Understanding implementation of quality improvement initiatives for maternal and newborn health: Exploring maternal and perinatal death audit

open access: yes, 2022
Master of Public Health - MPHPoor quality of health services contributes to high maternal and perinatal mortality, particularly in regions with the greatest burden of deaths, such as sub-Saharan Africa.
Kinney, Mary Virginia
core  

British National Formulary Guidance on prescribing in pregnancy: A descriptive cross‐sectional study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim To assess how well pregnancy‐specific guidance within the British National Formulary supports healthcare professionals to facilitate safe and effective medication use. Methods We performed a manifest content analysis of the text of all pregnancy sections within British National Formulary drug monographs, with inductive and iterative coding.
Hannah Johnson   +9 more
wiley   +1 more source

Report from nine maternal mortality review committees [PDF]

open access: yes
Approximately 700 women across the United States (U.S.) die each year as a result of pregnancy or pregnancy-related complications. Non-Hispanic black women experience maternal deaths at a rate three to four times that of non-Hispanic white women, a ...

core  

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

open access: yesBMEMat, EarlyView.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang   +12 more
wiley   +1 more source

GAMBARAN KEMATIAN MATERNAL DI RSUD DR. ZAINOEL ABIDIN SELAMA TAHUN 2010 DAN 2011

open access: yesJKS (Jurnal Kedokteran Syiah Kuala), 2013
Abstrak. Tujuan dari penelitian ini adalah untuk mengetahui distribusi kematian maternal di Rumah Sakit dr. Zainoel Abidin Banda Aceh dari bulan Januari 2010 sampai dengan Desember 2011.
Mohd Andalas   +3 more
doaj  

Counting cases, conserving species: addressing highly pathogenic avian influenza in wildlife

open access: yesBiological Reviews, EarlyView.
ABSTRACT Highly pathogenic avian influenza (HPAI) has become a critical threat to wildlife, shifting from a seasonal epizootic to a persistent, year‐round panzootic with global consequences. Here, we summarise the origin, evolutionary mechanisms, and expanding host range of the current H5N1 virus (clade 2.3.4.4b) and assess its impact on wildlife. Over
Ulrich Knief   +4 more
wiley   +1 more source

Buddhism, Brain Death and Organ Transplantation

open access: yes, 2010
This article raises concerns about the degree to which potential donors are aware that their layman‖s understanding of death may not be the same as that enshrined in protocols employing the criterion of brain death.
Keown, Damien V.
core  

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