Results 211 to 220 of about 443,472 (266)

Setting up mother–infant pair lactation studies with biobanking for research according to regulatory requirements

British Journal of Clinical Pharmacology, EarlyView.
Within the ConcePTION project we set out to design two mother–infant pair studies collecting breast milk and plasma from the mother and plasma from the infant (for metformin and prednisolone) in order to demonstrate the premises and conditions for investigating potential drug transfer in association with breastfeeding.
Mats Hansson, Ida Björkgren, Jenny Svedenkrans, Helena Backman, Jarl Hellman, Linda Englund‐Ögge, Mikaela Magnusson, Inger Lindström, Andrea Wutte, Erica Sundell, Pawel Baranczewski, Laura Shaughnessy   +11 more
wiley   +1 more source

Population pharmacokinetics of levofloxacin in breastmilk in patients with rifampicin‐resistant tuberculosis

British Journal of Clinical Pharmacology, EarlyView.
Levofloxacin is a widely used antibiotic included in rifampicin‐resistant tuberculosis (RR‐TB) treatment. Data describing levofloxacin concentrations in breastmilk and infant exposure are limited. We analysed data from two South African studies of breastfeeding women receiving levofloxacin (750–1000 mg daily) for RR‐TB.
Sharon Sawe, Lufina Tsirizani, Buyisile Mkhize, Lubbe Wiesner, Gary Maartens, Francesca Conradie, Richard Court, Marian Loveday, Catriona Waitt, Paolo Denti   +9 more
wiley   +1 more source

Zuranolone: A case study in (regulatory) rush to judgement?

British Journal of Clinical Pharmacology, EarlyView.
Abstract Sage, in collaboration with Biogen, submitted a new drug approval for zuranolone for postpartum depression (PPD) and major depressive disorder (MDD) in December 2022. In August 2023, the US Food and Drug Administration granted approval for PPD but denied approval for MDD.
Lisa Cosgrove, Milutin Kostic, Barbara Mintzes, Gianna D'Ambrozio, Allen Shaughnessy   +4 more
wiley   +1 more source

Infant negative affect, maternal intrusiveness, and child outcomes: The moderating role of maternal mind-mindedness in shaping psychopathology risk or resilience. [PDF]

Infant Ment Health J
Terehovsky Hagai BE, Einziger T, Frenkel TI.   +2 more
europepmc   +1 more source

Resilience in the early postpartum period: Buffering the impact of maternal ACEs on infant socioemotional development. [PDF]

Infant Ment Health J
Pattison M, Giles L, Gill S, Tulipan T, Campbell-Yeo M, Allen VM, Perrot T, Khoury JE.   +7 more
europepmc   +1 more source

Paediatric developmental safety and the ICH E11A extrapolation of safety

British Journal of Clinical Pharmacology, EarlyView.
Gilbert J. Burckart, Susan M. Abdel‐Rahman, Gelareh Abulwerdi, Rebecca Racz, Sherbet Samuels, Dionna J. Green, Lynne P. Yao   +6 more
wiley   +1 more source

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The adaptive significance of maternal effects

Trends in Ecology and Evolution, 1998
Recently, the adaptive significance of maternal effects has been increasingly recognized. No longer are maternal effects relegated as simple `troublesome sources of environmental resemblance' that confound our ability to estimate accurately the genetic basis of traits of interest.
Timothy A Mousseau, Charles W Fox
exaly   +3 more sources

The effects of maternal age and parity on maternal and neonatal outcome

Archives of Gynecology and Obstetrics, 2014
Delayed childbearing is increasingly common; hence, concerns emerge regarding potential for additional risks of delivery at advanced maternal age (AMA; ≥35 years). In this study, we sought to assess impact of AMA and parity on maternal and perinatal outcomes.In this retrospective single-center study (July 2005 to October 2011), we compared ...
Michael S, Schimmel, Ruben, Bromiker, Cathy, Hammerman, Lila, Chertman, Alexander, Ioscovich, Sorina, Granovsky-Grisaru, Arnon, Samueloff, Deborah, Elstein   +7 more
openaire   +2 more sources

The effect of maternal depression on maternal ratings of child behavior

Journal of Abnormal Child Psychology, 1993
There have been continuing concerns about the extent to which maternal depression may influence maternal reports of child behavior. To examine this issue, a series of structural equation models of the relationships between maternal depression and errors in maternal reports of child behavior was proposed and tested.
D M, Fergusson, M T, Lynskey, L J, Horwood   +2 more
openaire   +2 more sources

Maternal effects in personality

Behavior Genetics, 1974
A sample of 98 families consisting of 589 subjects and composed of three generations were examined on three personality dimensions: psychoticism, extraversion, and neuroticism. In addition, each family was administered tests of social attitudes and social desirability.
openaire   +2 more sources