Results 91 to 100 of about 1,277,264 (308)

Correlation between intestinal flora and glucuronidase indexes and sex hormone levels and their diagnostic efficacy evaluation for premature ovarian failure

open access: yesBMC Women's Health
Background Premature ovarian failure (POF), affecting women under 40, is characterized by early loss of ovarian function with unclear pathogenesis.
Yun Zhang   +6 more
doaj   +1 more source

Evolution-informed maternal–infant health [PDF]

open access: yesNature Ecology & Evolution, 2017
Can applying an evolutionary perspective generate effective change in clinical care and/or public health policy? An evolution-informed research programme has changed practice on UK post-natal units and UK health policies on infant care over the past two decades.
openaire   +4 more sources

Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

open access: yesAdvanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang   +16 more
wiley   +1 more source

Epidemiology of congenital polydactyly and syndactyly in Hunan Province, China

open access: yesBMC Pregnancy and Childbirth
Objective To describe the prevalence and epidemiology of congenital polydactyly and syndactyly in Hunan Province, China, 2016–2020. Methods Data were obtained from the Birth Defects Surveillance System in Hunan Province, China, 2016–2020.
Xu Zhou   +10 more
doaj   +1 more source

Evaluation of the Impact of the Mother and Infant Health Project in Ukraine [PDF]

open access: yes
This paper exploits a unique opportunity to evaluate the impact of the quality change in the labor and delivery services on maternal and infant health. Since basic medical care has been universally available in Ukraine, implementation of the Mother and ...
Maria Vyshnya, Olena Nizalova
core   +3 more sources

Community-based Approach to Intermittent Preventive Treatment for Malaria in Pregnancy in Kisumu, Kenya [PDF]

open access: yes, 2014
Malaria in pregnancy (MiP) is a significant contributor to maternal and newborn morbidity and mortality. In malaria-endemic countries, especially those in tropical areas of Africa where there is intense transmission of Plasmodium falciparum (P ...

core  

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

open access: yesAdvanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao   +7 more
wiley   +1 more source

Maternal Preconception Antibiotic Exposure Disrupts Microbial Succession: A Transgenerational Risk for Offspring Gut Mucosal Immaturity and Colitis Susceptibility

open access: yesAdvanced Science, EarlyView.
This study reveals that maternal antibiotic exposure prior to conception disrupts intergenerational gut microbial succession. By enhancing maternal‐offspring microbial transmission, altering microbial developmental trajectories and increasing selective pressures during community assembly, these disturbances lead to persistent gut mucosal immaturity and
Yuzhu Chen   +8 more
wiley   +1 more source

Analysis of human papillomavirus infection and its correlation with cervical lesions in Huizhou women

open access: yesScientific Reports
To analyze the genotype distribution of human papillomavirus (HPV) infection in women in the Huizhou region of China and determine its correlation with age and degree of cervical lesions, with the aim to understand the characteristics of HPV infection in
Xiaoting Wang   +5 more
doaj   +1 more source

The Role of Maternal Cognitive Ability in Child Health [PDF]

open access: yes
The literature on child health suggests mother`s schooling is a key determinant of child health. Little is known of how other sources of maternal human capital contribute to her children`s health. This paper investigates the differential returns on child
Graciela Teruel, Luis Rubalcava
core  

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