Results 51 to 60 of about 532,851 (307)

SOCIAL DETERMINANTS OF HEALTH AFFECTING UTILIZATION OF MATERNAL HEALTH SERVICES IN AFRICA: A NARRATIVE REVIEW

International Journal of Health Services Research and Policy, 2020
Despite improvements in maternal health, Sub-Saharan Africa countries still experience high maternal deaths. The provision of quality maternal health services has been adopted as a key strategy to reduce maternal mortality. However, low utilization rates
Ronald MUSIZVINGOZA
doaj   +1 more source

Precision Family Spirit: a pilot randomized implementation trial of a precision home visiting approach with families in Michigan—trial rationale and study protocol

Pilot and Feasibility Studies, 2021
Background Home visiting is a well-supported strategy for addressing maternal and child health disparities. However, evidence-based models generally share implementation challenges at scale, including engagement and retention of families.
Allison Ingalls, Allison Barlow, Elizabeth Kushman, Amanda Leonard, Lisa Martin, Precision Family Spirit Study Team, Allison L. West, Nicole Neault, Emily E. Haroz   +8 more
doaj   +1 more source

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

Advanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang, Emilie Derisoud, Denise Parreira, Nayere Taebnia, Paulo R. Jannig, Reza Zandi Shafagh, Allan Zhao, Congru Li, Macarena Ortiz, Manuel Alejandro Maliqueo, Elisabet Stener‐Victorin, Volker M. Lauschke, Qiaolin Deng   +12 more
wiley   +1 more source

Maternity waiting homes in Southern Lao PDR : the unique \u27silk home\u27

, 2008
The concept of maternity waiting homes (MWH) has a long history spanning over 100 years. The research reported here was conducted in the Thateng District of Sekong Province in southern Lao People’s Democratic Republic (PDR) to establish whether the
AbouZahr, Bryman, Cummins, Eckermann, Government of Lao PDR, Government of Lao PDR and UN, Population Reference Bureau, UNICEF, United Nations, United Nations Millennium Project, World Health Organization, World Health Organization, World Health Organization   +12 more
core   +1 more source

A framework for healthcare interventions to address maternal morbidity. [PDF]

, 2018
The maternal health agenda is undergoing a paradigm shift from preventing maternal deaths to promoting women's health and wellness. A critical focus of this trajectory includes addressing maternal morbidity and the increasing burden of chronic and ...
Adanu, Richard, Barreix, Maria, Cecatti, Jose G, Chou, Doris, Costa, Maria L, Filippi, Veronique, Firoz, Tabassum, Magee, Laura A, McCaw-Binns, Affette, members of the WHO Maternal Morbidity Working Group (MMWG), Say, Lale   +10 more
core   +1 more source

HRS Degradation‐Induced Nicotinamide Deficiency in Placental Extracellular Vesicles Triggers Preeclampsia by Disrupting Maternal‐Fetal Immune Homeostasis

Advanced Science, EarlyView.
This study shows that lower NAM levels in PE‐derived pEVs correlate with disease severity. NAM‐deficient pEVs reduce Th1 and Th17 inhibition, leading to PE‐like symptoms. NAM in pEVs inhibits Th1 via SIRT1 and Th17 via macrophages. Reduced NAM in PE‐EVs is due to decreased HRS expression in trophoblasts, resulting from elevated HSP27.
Haiyi Fei, Yuhan Lin, Xiu Liu, Xiaohong Zhu, Xiaowen Lu, Zhan Shi, Fan Jia, Shiqian Xu, Ling Fang, Lingling Jiang, Songying Zhang   +10 more
wiley   +1 more source

The Contribution of Public Health Center to Reducing Maternal Mortality [PDF]

, 2016
Backgroud: The health problems can be described on the number of Maternal Mortality (MMR), the higher of MMR toindication of so many health problems. Maternal mortality is closely related to access of quality health care.
Irianto, J. (Joko), Suharjo, S. (Suharjo)   +1 more
core   +1 more source

Caspase‐3/GSDME‐Mediated Trophoblast Pyroptosis and Reciprocal Macrophage Polarization Contribute to Inflammation in Early‐Onset Preeclampsia

Advanced Science, EarlyView.
In trophoblast cells, T/S (TNFα + SM164) activated caspase‐3, which cleaved GSDME to switch apoptosis to pyroptosis, causing cell swelling, membrane rupture, and release of LDH, HMGB1, IL‐1β and IL‐18. These cytokines induced pro‐inflammatory macrophage polarization, which in turn reinforced pyroptotic signaling in trophoblasts, amplifying systemic ...
Baoying Huang, Weinan Deng, Shilei Bi, Yifan Wang, Zhaowei Tu, Lijun Huang, Lili Du, Lizi Zhang, Zhoushan Feng, Wei Sun, Tengfei Liu, Julia Kzhyshkowska, Haibin Wang, Jingsi Chen, Dunjin Chen, Shuang Zhang   +15 more
wiley   +1 more source

Determinants of maternal health services utilization in Uganda [PDF]

BMC Health Services Research, 2015
Los deficientes indicadores de salud materna de Uganda se han debido a la deficiente prestación de servicios de salud materna, incluido el acceso a la planificación familiar de calidad, la asistencia cualificada al parto, la atención obstétrica de emergencia y la atención posnatal para madres y recién nacidos.
Gideon Rutaremwa, Stephen Ojiambo Wandera, Tapiwa Jhamba, Edith Akiror, Angela Kiconco   +4 more
openaire   +2 more sources

Monoaminylation in Human Health and Disease: State of the Field, Challenges, and Emerging Directions

Advanced Science, EarlyView.
This review delineates monoaminylation—serotonylation, dopaminylation, and histaminylation—as key post‐translational modifications beyond receptor signaling. It details their catalytic mechanisms, roles in gene expression and protein function, and implications in health and disease, aiming to bridge mechanistic insights with therapeutic potential ...
Yiqi Zhao, Hongli Zhang, Yating Yang, Wei‐Dong Chen, Yan‐Dong Wang   +4 more
wiley   +1 more source