Results 201 to 210 of about 3,104,714 (298)

Conducting clinical lactation trials in the United Kingdom—Reflections from the New Horizons clinical trial

British Journal of Clinical Pharmacology, EarlyView.
Jignesh P. Patel, Roopen Arya
wiley   +1 more source

Model‐Informed Dose Optimization of Anakinra in Preterm Neonates Implications for Safe and Effective Dosing

Clinical Pharmacology &Therapeutics, EarlyView.
Anakinra, an interleukin‐1 receptor antagonist, shows promise for reducing inflammatory complications of premature birth. However, the pharmacokinetics (PK) of anakinra in neonates has not been characterized, limiting evidence‐based dosing. This study aimed to develop a population PK model for anakinra to guide dosing in preterm neonates.
Jia Li, David K. Metz, Elys Green, Gergely Toldi, Robert Galinsky, Megan Clark, Rebecka Atkinson, Ina Rudloff, Josephine C. Owen, Sara K. DiSimone, Samuel C. Forster, Steven X. Cho, Atif Majid, Graeme R. Polglase, Marcel Favilla, Pramod Pharande, Atul Malhotra, Calum T. Roberts, Scott H. Stansfield, Arvind Sehgal, Kenneth Tan, Alistair J. Gunn, Philip J. Berger, Alex Veldman, Rod W. Hunt, Claudia A. Nold‐Petry, Marcel F. Nold, Carl M. J. Kirkpatrick   +27 more
wiley   +1 more source

Medication Use During Breastfeeding—An Understudied Population: A Five‐Year Experience in the Pharmacovigilance Center of Lyon

Clinical Pharmacology &Therapeutics, EarlyView.
Medication use during breastfeeding is common, yet data on drug transfer into breast milk and infant exposure remain limited. This study describes real‐world requests concerning medication compatibility with breastfeeding managed by the Lyon pharmacovigilance center over five years.
Blandine Bertin, Aurore Gouraud, Anthony Facile, Fanny Ledys, Sabrina Pierre, Véronique Pizzoglio, Thierry Vial, Marine Auffret, Marina Atzenhoffer   +8 more
wiley   +1 more source

Establishment of pediatric reference ranges for circulating naïve and memory T and B cell subsets guided by the human immunophenotyping consortium standardization initiative: A large, single center U.S. experience

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Our knowledge of the immune system continues to expand at a rapid pace, and this coupled with technological advances now enables us to interrogate both the breadth and the depth of the immune response at levels without precedent. This has also facilitated rapidly integrating some of this carefully vetted knowledge into clinical practice ...
Aaruni Khanolkar, Aisha Ahmed
wiley   +1 more source

Seroprevalence of <i>Toxoplasma gondii</i>, Rubella Virus, Cytomegalovirus, and Herpes Simplex Virus Among Children and Women in Bhutan's National Referral Hospital: A Cross-Sectional Study. [PDF]

Public Health Chall
Norbu K, Rabjay SW, Galey K, Dorji T, Chophel U, Wangmo J, Rai B, Dorjey Y, Tshokey T.   +8 more
europepmc   +1 more source

Threats to Public Health and Scientific Infrastructures Threaten Progress in Eating Disorder Research, Treatment, and Prevention: A Call to Action for the Field

International Journal of Eating Disorders, EarlyView.
ABSTRACT The US federal government has enacted sweeping policy changes since January 2025 that imperil public health, with important implications for the eating disorders field—a field that is already disproportionately under‐resourced. This paper examines the pathways through which these recent policy changes threaten progress in eating disorder ...
Ariel L. Beccia, Lilian P. Palmer, Bek Urban, Amanda Raffoul   +3 more
wiley   +1 more source

Adverse Maternal Outcomes of Cesarean Section: Prevalence, Complications, and Predictors Among Mothers Who Underwent Cesarean Delivery at Yirgalem General Hospital, Sidama Region, Ethiopia - A Cross-Sectional Study. [PDF]

Health Serv Insights
Dona A, Assefa K, Bolka A.
europepmc   +1 more source