Results 41 to 50 of about 576,135 (348)

TP53BP2 Promotes Placental Autophagy and Preeclampsia via G9a and DNMT1 Cooperatively Modulating E2F1

Advanced Science, EarlyView.
G9a, and DNA Methyltransferase1 (DNMT1) cooperatively modulates E2F1 on the promoter of tumor suppressor p53‐binding protein 2 (TP53BP2) increased autophagy in preeclampsia. TP53BP2 promotes autophagy in trophoblasts through DNA methylation and H3K9me2‐mediated transcriptional regulation.
Nan Jiang, Shaoju Jin, Shaoying Wen, Wen Zeng, Chen Wang, Jingyu Wang, Qingyun Song, Guizhong Li, Pengzhi Yin, Yuhui Liao, Yuee Chai, Huiping Zhang, Shengchao Ma   +12 more
wiley   +1 more source

Maternal mortality in a tertiary care hospital: A 10-year review

International Journal of Preventive Medicine, 2013
Background: Epidemiological data pertaining to maternal mortality is valuable in each set up to design interventional programs to favourably reduce the ratio.
Bhaskar K Murthy, Mangala B Murthy, Priya M Prabhu   +2 more
doaj  

Measuring Maternal Mortality: Three Case Studies Using Verbal Autopsy with Different Platforms. [PDF]

PLoS ONE, 2015
Accurate measurement of maternal mortality is needed to develop a greater understanding of the scale of the problem, to increase effectiveness of program planning and targeting, and to track progress.
Siân L Curtis, Robert G Mswia, Emily H Weaver   +2 more
doaj   +1 more source

Reducing Maternal Mortality [PDF]

, 2010
Outlines MacArthur's efforts to reduce maternal mortality mainly in Mexico, Nigeria, and India by funding projects to develop scalable models, enhance health workers' skills, promote informed advocacy, and advance research.

core  

Peripartum infections and associated maternal mortality in rural Malawi [PDF]

, 2011
Article approval pendingTo assess associations between maternal mortality and severe morbidity and human immunodeficiency virus (HIV) infection, uptake of antiretroviral therapy, obstetric infections, and nonobstetric infections in a rural Malawian ...
Ahmad, Beatrice Mwagomba, Bemelmans, Bryant, Chiphangwi, Denny, Ford, Hogan, Jahn, Jos van Roosmalen, Lapaire, Louis, McIntyre, Mehta, Moodley, Mwagomba, Nathan Ford, Pollack, Semprini, Stefan de Vroome, Thomas van den Akker, van den Akker, Walson, Zachariah   +23 more
core   +3 more sources

Caspase‐3/GSDME‐Mediated Trophoblast Pyroptosis and Reciprocal Macrophage Polarization Contribute to Inflammation in Early‐Onset Preeclampsia

Advanced Science, EarlyView.
In trophoblast cells, T/S (TNFα + SM164) activated caspase‐3, which cleaved GSDME to switch apoptosis to pyroptosis, causing cell swelling, membrane rupture, and release of LDH, HMGB1, IL‐1β and IL‐18. These cytokines induced pro‐inflammatory macrophage polarization, which in turn reinforced pyroptotic signaling in trophoblasts, amplifying systemic ...
Baoying Huang, Weinan Deng, Shilei Bi, Yifan Wang, Zhaowei Tu, Lijun Huang, Lili Du, Lizi Zhang, Zhoushan Feng, Wei Sun, Tengfei Liu, Julia Kzhyshkowska, Haibin Wang, Jingsi Chen, Dunjin Chen, Shuang Zhang   +15 more
wiley   +1 more source

Maternal Mortality in a Tertiary Care Hospital: A Five Year Review

Journal of Rawalpindi Medical College, 2018
Background: To find out the maternal mortality in a tertiary care hospital. Methods: In this retrospective study, data regarding maternal mortality was collected .
Rizwana Anjum et al.,
doaj  

miR‐135a‐5p Is a Promising Target to Prevent the Glomerulosclerosis Associated with Podocyte Developmental Toxicity in Offspring Induced by Prenatal Dexamethasone Exposure

Advanced Science, EarlyView.
Prenatal dexamethasone exposure (PDE) programs persistent podocyte developmental injury and adult glomerulosclerosis. Mechanistically, glucocorticoid receptor (GR) binds the miR‐135a‐5p promoter and recruits the histone acetyltransferase p300, increasing promoter histone acetylation and sustaining miR‐135a‐5p expression. Elevated miR‐135a‐5p suppresses
Xiaoqi Zhao, Haiyun Chen, Yanan Zhu, Zhiping Xia, Hangyuan He, Yutang Liu, Tianshu Yang, Hui Wang, Ying Ao   +8 more
wiley   +1 more source

Pro-poor policies and improvements in maternal health outcomes in India

BMC Pregnancy and Childbirth, 2021
Background Since 2005, India has experienced an impressive 77% reduction in maternal mortality compared to the global average of 43%. What explains this impressive performance in terms of reduction in maternal mortality and improvement in maternal health
M. Bhatia, L. K. Dwivedi, K. Banerjee, A. Bansal, M. Ranjan, P. Dixit   +5 more
doaj   +1 more source

Safe abortion – Still a neglected scenario: A study of septic abortions in a tertiary hospital of Rural India [PDF]

, 2010
Background and Aims: In spite abortion has been legalized in India over three decades, unsafe abortion continues to be a significant contributor of maternal mortality and morbidity.
Bhattacharya, S, Mistri, P, Mukherjee, G, Pati , S   +3 more
core   +1 more source