Results 41 to 50 of about 531,213 (333)

Peripartum infections and associated maternal mortality in rural Malawi [PDF]

, 2011
Article approval pendingTo assess associations between maternal mortality and severe morbidity and human immunodeficiency virus (HIV) infection, uptake of antiretroviral therapy, obstetric infections, and nonobstetric infections in a rural Malawian ...
Ahmad, Beatrice Mwagomba, Bemelmans, Bryant, Chiphangwi, Denny, Ford, Hogan, Jahn, Jos van Roosmalen, Lapaire, Louis, McIntyre, Mehta, Moodley, Mwagomba, Nathan Ford, Pollack, Semprini, Stefan de Vroome, Thomas van den Akker, van den Akker, Walson, Zachariah   +23 more
core   +3 more sources

Suicide and Maternal Mortality

Current Psychiatry Reports, 2022
Suicide is a leading cause of death in the perinatal period (pregnancy and 1 year postpartum). We review recent findings on prevalence, risk factors, outcomes, and prevention and intervention for suicide during pregnancy and the first year postpartum.Standardization of definitions and ascertainment of maternal deaths have improved identification of ...
Chin, Kathleen, Wendt, Amelia, Bennett, Ian M., Bhat, Amritha   +3 more
openaire   +2 more sources

Advances in Single‐Cell Sequencing for Infectious Diseases: Progress and Perspectives

Advanced Science, EarlyView.
Single‐cell sequencing technologies uncover novel, unknown, and emergent features of many diseases. This review describes recent progress of single‐cell sequencing technologies and their applications in infectious diseases, summarizes the underlying commonalities of different infections and discusses future research directions, facilitating the ...
Mengyuan Lyu, Yang Liu, Jian Zhou, Hongli Lai, Hongxia Ruan, Dongsheng Wu, Shun Zhu, Xudong Zhou, Wananqi Ma, Yuchen Huang, Shuting Lei, Han Luo, Jie Chen, Binwu Ying   +13 more
wiley   +1 more source

Levels and determinants of maternal mortality in northern and southern Nigeria

BMC Pregnancy and Childbirth, 2019
Background Maternal mortality is still a major risk for women of childbearing age in Nigeria. In 2008, Nigeria bore 14% of the global burden of maternal mortality.
Catherine Meh, Amardeep Thind, Bridget Ryan, Amanda Terry   +3 more
doaj   +1 more source

Localized Delivery of the mRNAs Encoding CD47 Inhibitor and Interleukins 12, 15, and 21 Elicits Robust Antitumor Immunity

Advanced Science, EarlyView.
The co‐delivery of mRNAs encoding a CD47 inhibitor and a cytokine cocktail (interleukins 12, 15, and 21) via lipid nanoparticles enables effective localized immunotherapy. This strategy not only suppresses tumor progression but also enhances type 1 conventional dendritic cell (cDC1) differentiation and activates CD8+ T cells, thereby inducing robust ...
Tao Jiang, Shuaiyang Jing, Haojun Li, Bao Xiao, Jiahui Jin, Xiu Sun, Juan Wang, Jing Liang, Tongze Cai, Huili Hu, Meilan Wei, Xuanrui Zhong, Yang Ji, Peng George Wang, Jianlong Zhou   +14 more
wiley   +1 more source

Incidence and Predictors of Maternal and Perinatal Mortality among Women with Severe Maternal Outcomes: A Tanzanian Facility-Based Survey for Improving Maternal and Newborn Care

Obstetrics and Gynecology International, 2020
Introduction. Maternal and perinatal mortality is still a major public health challenge in Tanzania, despite the ongoing government efforts to improve maternal and newborn care.
Athanase Lilungulu, Deogratius Bintabara, Simon Mujungu, Enid Chiwanga, Paulo Chetto, Mzee Nassoro   +5 more
doaj   +1 more source

PCSK9 Loss‐of‐Function Disrupts Cellular Microfilament Network via LIN28A/HES5/JMY Axis in Neural Tube Defects

Advanced Science, EarlyView.
PCSK9 acts as a molecular chaperone promoting LIN28A lysosomal degradation. LIN28A elevates transcription factor HES5, increasing JMY expression. PCSK9 loss causes neural tube defects (NTDs) by disrupting the LIN28A/HES5/JMY axis, and high JMY disorganizes the neural progenitor cell microfilament network, leading to incomplete neural tube structure in ...
Xiaoshuai Li, Rui Wang, Wenting Luo, Hui Gu, Tianchu Huang, Qiushi Wang, Zhengwei Yuan   +6 more
wiley   +1 more source

Maternal health and child mortality in rural India [PDF]

In this paper, the effect of maternal health on the under-five mortality has been examined. Third wave of micro-level National Family Health Survey 2005-06 data for rural India is used.
Pandey, Manoj K.
core   +4 more sources

ADAR1 as a Placental Innate Immune Rheostat Sustaining the Homeostatic Balance of Intrinsic Interferon Response at the Maternal‐Fetal Interface

Advanced Science, EarlyView.
This study reveals that ADAR1, an RNA‐editing enzyme, fine‐tunes immune responses in the placenta by preventing the accumulation of immunogenic double‐stranded RNAs (dsRNAs) from interferon‐stimulated genes. The loss of ADAR1 in the placenta leads to excessive interferon signaling restricted to the junctional zone, disrupting placental development and ...
Xiaogang Chen, Xiangchao Xu, Jiahao Chen, Huiru Zhang, Wanshan Zheng, Wenzhe Yu, Xiaoqian Hu, Bin Cao   +7 more
wiley   +1 more source

Maternal Mortality in a Tertiary Care Hospital: A Five Year Review

Journal of Rawalpindi Medical College, 2018
Background: To find out the maternal mortality in a tertiary care hospital. Methods: In this retrospective study, data regarding maternal mortality was collected .
Rizwana Anjum et al.,
doaj