Results 81 to 90 of about 2,123,633 (258)

Zuranolone: A case study in (regulatory) rush to judgement?

British Journal of Clinical Pharmacology, EarlyView.
Abstract Sage, in collaboration with Biogen, submitted a new drug approval for zuranolone for postpartum depression (PPD) and major depressive disorder (MDD) in December 2022. In August 2023, the US Food and Drug Administration granted approval for PPD but denied approval for MDD.
Lisa Cosgrove, Milutin Kostic, Barbara Mintzes, Gianna D'Ambrozio, Allen Shaughnessy   +4 more
wiley   +1 more source

Global, regional, and national levels of maternal mortality, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015

, 2016
Background In transitioning from the Millennium Development Goal to the Sustainable Development Goal era, it is imperative to comprehensively assess progress toward reducing maternal mortality to identify areas of success, remaining challenges, and frame
GBD 2015 Maternal Mortality Collaborators (7807730)
core   +2 more sources

Severe Obstetric Morbidity: Prevalence, Risk Factors and Outcome

National Journal of Community Medicine, 2015
Background: Severe Obstetric Morbidity (SOM) can be a supple- mentary indicator to maternal mortality. We have very little in- formation about its prevalence and risk factors.
Reena RP, Umadevi N, Ajitha BK
doaj  

Achieving the Millennium Development Goal of reducing maternal mortality in rural Africa: an experience from Burundi. [PDF]

, 2012
OBJECTIVES: To estimate the reduction in maternal mortality associated with the emergency obstetric care provided by Médecins Sans Frontières (MSF) and to compare this to the fifth Millennium Development Goal of reducing maternal mortality.
Nicolai, M, Van den Boogaard, W, Manzi, M, Harries, AD, Christaens, B, Manirampa, J, Harries, A D, Ndelema, B, Van den Bergh, R, Nyandwi, G, Zachariah, R, Tayler-Smith, K, De Plecker, E, Goetghebuer, S, Lambert, V, Reid, T, Kabangu, A   +16 more
core   +1 more source

A Retrospective Study On Maternal Deaths And Its Causes In A Tertiary Care Teaching Institute In Northern Telangana

Perspectives In Medical Research, 2019
Background: Maternal mortality is a strong indicator for measuring the health care provided to the women by any society. Although pregnancy is considered physiological at times it leads to morbidity and even death.
Satyaprabha S1, Vivekananda A2, Mythreai3, Wilson V4
doaj  

Dose‐related propofol resistance in COVID‐19 patients: Altered drug plasma levels, mechanistic insights from neuronal‐derived extracellular vesicles and miRNA analysis

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Critical care for COVID‐19 patients presents unique challenges, particularly in sedation management. Patients demonstrate notable dose‐related resistance to propofol, potentially due to complex pharmacokinetic alterations. Emerging evidence suggests that plasma extracellular vesicle‐associated miRNA represents valuable predictive ...
Debora Curci, Carlotta Bidoli, Marco Gerdol, Charisse Winston, Robert A. Rissman, Giuliana Decorti, Antonella Fabretto, Andrea Taddio, Gabriele Stocco, Erik Roman‐Pognuz, Marianna Lucafò   +10 more
wiley   +1 more source

A Bayesian Approach to Estimate Maternal Mortality Globally Using National Civil Registration Vital Statistics Data Accounting for Reporting Errors

Statistics and Public Policy
Estimation and monitoring of mortality, across multiple population-periods, is vital to improving national and global health outcomes. Reducing maternal mortality is a key part of the Sustainable Development Goals (SGDs), which commit countries and ...
Emily N. Peterson, Greg Guranich, Jenny A. Cresswell, Leontine Alkema   +3 more
doaj   +1 more source

Examining the ‘‘Urban Advantage’’ in maternal health care in developing countries [PDF]

, 2010
As the global urban population surpasses the rural, continuing growth in most developing countries means an inevitable increase in urban births. The majority of births in many countries will not be in remote rural areas, but in towns and cities [1].
Osrin, David, Matthews Zoë, Matthews, Zoe, Madise, Nyovani, Amos Channon, William Stones, David Osrin, Madise Nyovani, Stones, William, Channon Amos, Nyovani Madise, Osrin David, Neal Sarah, Channon, Amos, Zoë Matthews, Stones William, Neal, Sarah, Sarah Neal, Channon, Andrew A.R.   +18 more
core   +1 more source

Lithium‐related adverse drug reactions in children: A case–control study comparing lithium to second‐generation antipsychotics in VigiBase

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to improve the understanding of lithium's safety profile by analysing the frequency and distribution of reported adverse drug reactions (ADRs) compared to second‐generation antipsychotics (SGAs). Methods Individual case safety reports from VigiBase (1968–October 2023) involving individuals older than 2 years, with lithium or SGAs ...
Lisa T. Ringeling, Ravish N. Gangapersad, Lillian Lieuw, Patrick C. Souverein, Eibert R. Heerdink, Pilar Garcia‐Gomez, Manon H. J. Hillegers, Birgit C. P. Koch, Bram Dierckx   +8 more
wiley   +1 more source

“Near Miss” Obstetric Events and Maternal Deaths in a Tertiary Care Hospital: An Audit

Journal of Pregnancy, 2013
Objectives. (1) To determine the frequency of maternal near miss, maternal near miss incidence ratio (MNMR), maternal near miss to mortality ratio and mortality index. (2) To compare the nature of near miss events with that of maternal mortality.
Roopa PS, Shailja Verma, Lavanya Rai, Pratap Kumar, Murlidhar V. Pai, Jyothi Shetty   +5 more
doaj   +1 more source