Results 51 to 60 of about 4,625,019 (257)

A Metabolic‐Epigenetic Axis of AARS1/IGF2BP3‐K280 Lactylation Sustains Endometrial Cancer Stemness and Recurrence

Advanced Science, EarlyView.
Lactate‐driven endometrial cancer relapse is mediated by enzymatic protein modification. Elevated lactate levels activate AARS1, which catalyzes K280 lactylation of IGF2BP3, therefore stabilizing HMGA2 mRNA and promoting tumor stemness and recurrence.
Peng Jiang, Yunfeng Zheng, Chenfan Tian, Yuan Tu, Xiaoxia Chang, Jiaxin Yu, Hangkun Yu, Chunxia Gong, Jie Xiong, Philip N. Baker, Yong Fu, Chao Tong   +11 more
wiley   +1 more source

Contributing factors for reduction in maternal mortality ratio in India

Scientific Reports
AbstractMaternal mortality ratio (MMR) estimates have been studied over time for understanding its variation across the country. However, it is never sufficient without accounting for presence of variability across in terms of space, time, maternal and system level factors.
Himanshu Tolani, Sutapa Bandyopadhyay Neogi, Anuj Kumar Pandey, Pijush Kanti Khan, Sidharth Sekhar Mishra   +4 more
openaire   +3 more sources

Oregon Maternal Mortality and Morbity Review Committee biennial report

, 2021
Maternal and Child Health Section of the Center for Prevention & Health Promotion within the Public Health Division of the Oregon Health Authority.Began with [2020]."In accordance with Oregon House Bill 4133, Chapter 63, 2018 Oregon Laws Section 1.

core  

BRCA1 Mutation‐Recognizing Tetrahedral Framework Nucleic Acid Nanoplatform Enables Coordinated PARP/WEE1 Inhibition and STING‐Associated Antitumor Immunity in Ovarian Cancer

Advanced Science, EarlyView.
BRCA1 mutation‐responsive FBOA‐tFNA selectively recognizes mutant transcripts and coordinates reduction‐responsive intracellular delivery of olaparib and adavosertib, amplifying DNA damage and weakening G2/M checkpoint protection. These effects are accompanied by STING‐associated immune activation and stronger antitumor immunity, while sequential anti ...
Chenyi Wang, Mengying Yao, Jinhui Xie, Dingjie Wang, Yashi Shi, Xiaodan Mao, Chunhua Lu, Pengming Sun   +7 more
wiley   +1 more source

Maternal mortality in jos nigeria: a facility based prospective review [PDF]

International Journal of Biological and Medical Research, 2011
Objectives The study was designed to determine the maternal mortality ratio at the Jos University teaching Hospital and ascertain the causes of maternal death.
Stephen D. Ngwan, Terrumun Z. Swende
doaj  

Public health approach to address maternal mortality

Indian Journal of Public Health, 2012
Reducing maternal mortality is one of the major challenges to health systems worldwide, more so in developing countries that account for nearly 99% of these maternal deaths.
Sanjay K Rai, K Anand, Puneet Misra, Shashi Kant, Ravi Prakash Upadhyay   +4 more
doaj   +1 more source

Maternal mortality ratio (MMR) in Bangladesh.

, 2019
Maternal mortality ratio (MMR) in Bangladesh.
Pete E. Lestrel (6470267), Md. Golam Hossain (6470264), Sultana Rajia (6470258), Md. Sabiruzzaman (6470261), Md. Kamrul Islam (3855025)   +4 more
core   +1 more source

Maternal tetanus toxoid vaccination and neonatal mortality in rural North India [PDF]

, 2015
Objectives: Preventable neonatal mortality due to tetanus infection remains common. We aimed to examine antenatal vaccination impact in a context of continuing high neonatal mortality in rural northern India.
Singh, Abhishek, William Stones, Ogollah, Reuben, Stones, William, Reuben Ogollah, Pallikadavath, Saseendran, Saseendran Pallikadavath, Abhishek Singh   +7 more
core   +3 more sources

Systematic Cardiac Phenotyping of Patients With Copy Number Variants in the 15q11.2 Breakpoint 1 to Breakpoint 2 Region: A Retrospective Cohort Study From Nine Pediatric Cardiac Centers

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Microdeletions impacting 15q11.2 breakpoint (BP) 1 to BP2, adjacent to the Prader–Willi critical region, have previously described neuropsychiatric associations, with potential low penetrance presentations of congenital heart disease (CHD) also identified.
Morgan B. Wright, Maria B. Padua, Lindsey R. Helvaty, Kim L. McBride, Gabrielle Geddes, Vidu Garg, Seema R. Lalani, Stephanie Burns Wechsler, Jennelle C. Hodge, Benjamin J. Landis, Stephanie M. Ware   +10 more
wiley   +1 more source

Maternal mortality ratio in Colombian municipalities, 2011.

, 2015
Maternal mortality ratio in Colombian municipalities, 2011.
Fernando De la Hoz-Restrepo (704964), Angel Paternina-Caicedo (704962), Pablo Enrique Chaparro-Narváez (704961), Karol Cotes-Cantillo (704960), Luz Mery Cárdenas-Cárdenas (704959), Julián Alfredo Fernández-Niño (633524), Carlos Castañeda-Orjuela (704963)   +6 more
core   +1 more source