Results 211 to 220 of about 2,548,288 (258)

Oral vancomycin solution is superior to capsule in inducing clinical biomarker and endoscopic remission in children with atypical ulcerative colitis

British Journal of Clinical Pharmacology, EarlyView.
Aims Atypical colitis (presenting reverse gradient colitis, backwash ileitis or rectal sparing) is associated with primary sclerosing cholangitis–ulcerative colitis (PSC). Oral vancomycin has been used to manage paediatric atypical colitis with/without confirmed PSC. Different preparations had shown different efficacy.
Laura Räisänen, Fariha Balouch, Claire Reilly, Christopher Burgess, Peter Lewindon   +4 more
wiley   +1 more source

Setting up mother–infant pair lactation studies with biobanking for research according to regulatory requirements

British Journal of Clinical Pharmacology, EarlyView.
Within the ConcePTION project we set out to design two mother–infant pair studies collecting breast milk and plasma from the mother and plasma from the infant (for metformin and prednisolone) in order to demonstrate the premises and conditions for investigating potential drug transfer in association with breastfeeding.
Mats Hansson, Ida Björkgren, Jenny Svedenkrans, Helena Backman, Jarl Hellman, Linda Englund‐Ögge, Mikaela Magnusson, Inger Lindström, Andrea Wutte, Erica Sundell, Pawel Baranczewski, Laura Shaughnessy   +11 more
wiley   +1 more source

Population pharmacokinetics of levofloxacin in breastmilk in patients with rifampicin‐resistant tuberculosis

British Journal of Clinical Pharmacology, EarlyView.
Levofloxacin is a widely used antibiotic included in rifampicin‐resistant tuberculosis (RR‐TB) treatment. Data describing levofloxacin concentrations in breastmilk and infant exposure are limited. We analysed data from two South African studies of breastfeeding women receiving levofloxacin (750–1000 mg daily) for RR‐TB.
Sharon Sawe, Lufina Tsirizani, Buyisile Mkhize, Lubbe Wiesner, Gary Maartens, Francesca Conradie, Richard Court, Marian Loveday, Catriona Waitt, Paolo Denti   +9 more
wiley   +1 more source

Zuranolone: A case study in (regulatory) rush to judgement?

British Journal of Clinical Pharmacology, EarlyView.
Abstract Sage, in collaboration with Biogen, submitted a new drug approval for zuranolone for postpartum depression (PPD) and major depressive disorder (MDD) in December 2022. In August 2023, the US Food and Drug Administration granted approval for PPD but denied approval for MDD.
Lisa Cosgrove, Milutin Kostic, Barbara Mintzes, Gianna D'Ambrozio, Allen Shaughnessy   +4 more
wiley   +1 more source

Adverse Maternal Outcomes of Cesarean Section: Prevalence, Complications, and Predictors Among Mothers Who Underwent Cesarean Delivery at Yirgalem General Hospital, Sidama Region, Ethiopia - A Cross-Sectional Study. [PDF]

Health Serv Insights
Dona A, Assefa K, Bolka A.
europepmc   +1 more source

Certified Nurse-Midwife Practice Authority as a Structural Determinant of Maternal Health. [PDF]

Milbank Q
Tucker CM, Baumstark J.
europepmc   +1 more source

Paediatric developmental safety and the ICH E11A extrapolation of safety

British Journal of Clinical Pharmacology, EarlyView.
Gilbert J. Burckart, Susan M. Abdel‐Rahman, Gelareh Abulwerdi, Rebecca Racz, Sherbet Samuels, Dionna J. Green, Lynne P. Yao   +6 more
wiley   +1 more source

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Maternal age and risk for adverse outcomes

American Journal of Obstetrics and Gynecology, 2018
(Am J Obstet Gynecol. 2018;219:390.e1–15) Over the past decade, the rate of births to women aged 30 years and older has risen. This trend will likely continue with the widespread availability of newer reproductive technologies. As women age, they are more likely to have comorbid conditions and women of advanced maternal age have increased ...
Alexander Friedman, Jason Wright, Mary E D'Alton   +2 more
exaly   +3 more sources

Maternal outcome in eclampsia at Harare Maternity Hospital

Central African Journal of Medicine, 2001
To study the presentation, management and determinants of maternal outcome in eclampsia at Harare Maternity Hospital (HMH) in order to design interventions for reduction of maternal mortality.Cross sectional descriptive study.Harare Maternity Hospital, Harare, Zimbabwe.All women with diagnosis of eclampsia treated at HMH during an 18 month period.The ...
Majoko, F, Mujaji, C
openaire   +3 more sources

Maternal obesity and infant outcomes

Early Human Development, 2010
Obesity (Body mass index (BMI) above 30) is one of the major health issues of the 21st century. Over 1.1 billion of the world's population are now classified as obese. In the UK, women are more likely to be obese than men; over 50% of women of reproductive age are overweight or obese.
Rikke, Ruager-Martin, Matthew J, Hyde, Neena, Modi   +2 more
openaire   +2 more sources