Advanced Science, EarlyView.Maternal exercise (ME) increases apelin abundance across maternal and fetal tissues and is associated with improved fetal osteogenesis under POLG mutation‐induced mitochondrial dysfunction. Apelin‐APJ signaling is linked to enhanced mitochondrial function, Akt phosphorylation, and ATF4‐RUNX2 association, supporting coordinated fetal bone remodeling ...
Song Ah Chae +5 more
wiley +1 more source
m6A‐Driven Pexophagy Triggers Placental Ferroptosis to Impair Fetal Growth Upon Environmental Stress
Advanced Science, EarlyView.Prenatal environmental stress exposure promotes m6A modification to drive PEX2‐dependent pexophagy, thereby causing placental ferroptosis and FGR. ABSTRACT The role and underlying mechanisms of placental ferroptosis in fetal growth restriction (FGR) induced by environmental stress remain poorly understood.
Xin‐Xin Zhang +18 more
wiley +1 more source
The Effect of Maternal Anemia on Low Birth Weight: A Systematic Review And Meta Analysis
, 2022 Background: Low birth weight (LBW) is a risk factor for morbidity and mortality in infants. Several previous studies have suggested that maternal anemia has an effect on several adverse perinatal outcomes, including low birth weight. The purpose of this
Azizah, Fara Khansa +2 more
core
Advanced Science, EarlyView.Androgenetic alopecia (AGA) is a common form of hair loss with limited treatment options. Silencing of WNT5A signaling, which is widely known as the trigger of the ncWNT signaling pathway, happens in hair follicle stem cells from balding areas. It leads to downregulation of ATF3 and its target FOSB.
Ruiyu Luo +10 more
wiley +1 more source
Effectiveness of the Expanded Maternal and Neonatal Survival Program in the Reduction of Maternal Mortality in Tegal, Central Java [PDF]
, 2016 Background: Maternal mortality rate is one of the sensitive indicators of population health in a country. Various measures have been implemented to reduce maternal mortality rate, including the Expanding Maternal And Neonatal Survival (EMAS) program ...
Demartoto, Argyo +2 more
core
The Association between Exclusive Breastfeeding, Maternal Nutritional Status, Maternal Zinc Intake, and Stunting in Infants Aged 6 Months [PDF]
, 2020 Background: Stunting is a form of malnutrition that has an impact on decreased learning achievement, motor and mental development and intellectual.
Salimo, Harsono +2 more
core
BOULE is Essential for the Dynamic Disassembly of Heat Shock Granules in Male Germ Cells
Advanced Science, EarlyView.BOULE orchestrates stress granule disassembly in germ cells via a two‐pronged mechanism: it promotes G3BP1 ubiquitination by upregulating TRIM27, generating a signal for VCP/FAF2 recruitment, and it maintains G3BP1 and FAF2 protein levels. BOULE deficiency disrupts disassembly complex formation, leading to impaired heat shock granule clearance ...
Xin Li +8 more
wiley +1 more source
A Five-Year Review of Feto-Maternal Outcome of Antepartum Haemorrhage in a Tertiary Center. [PDF]
Int J Innov Res Med Sci, 2023 Oguejiofor CB +13 more
europepmc +1 more source
Pre-eclampsia : predicting onset and poor outcome [PDF]
Pre-eclampsia is a pregnancy-specific, multi-system disorder of placental origin. Affecting between 2-8% of women, it is one of the leading causes of both maternal and fetal morbidity and mortality in the United Kingdom.
Breslin, Eamonn
core
NICE: A Two‐Step Non‐Invasive Framework for Embryo cfDNA Read Enrichment and Quality Assessment
Advanced Science, EarlyView.The non‐invasive NICE framework, built on an ensemble stacking machine learning model, prioritizes embryos by analyzing cell‐free DNA from spent culture medium. By integrating multimodal signals, including genomic and epigenetic profiles, this automated approach standardizes morphological assessment without human bias, paving the way for more precise ...
Xueya Zhou +6 more
wiley +1 more source