We established that mixed DdCBE microinjection is an efficient, heritable, and precise strategy for generating multiplex mtDNA mutant rats. This advancement significantly expands the utility of DdCBEs for mitochondrial disease modeling, providing a robust platform for exploring the pathogenic mechanisms of complex mtDNA mutations and developing ...
Xu Zhang +14 more
wiley +1 more source
Recent Trends in Metabolomics by NMR Spectroscopy
AI tools were applied to analyze more than 5 000 publications indexed in Scopus (2018–2025), identifying key trends and research directions in NMR‐based metabolomics. The artificial intelligence‐assisted workflow classified papers into six main fields of application, human health, food and nutrition, veterinary science, plants, environment, and ...
Giorgio Di Paco +6 more
wiley +2 more sources
Malaria prophylaxis stock-outs and birth- and maternal outcomes in Zimbabwe. [PDF]
Chari A, Burger R, von Fintel D.
europepmc +1 more source
Equine models in translational medicine: A comparative approach to human health
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh +1 more
wiley +1 more source
Maternal Outcomes and Resource Utilization in Pregnancy-Related Hospitalizations Among Patients With Irritable Bowel Syndrome: A Nationwide Inpatient Analysis, 2020-2022. [PDF]
Latif MH +6 more
europepmc +1 more source
Clotrimazole‐loaded PLGA microparticles for local drug delivery to the vagina: Shape does matter
Clotrimazole‐loaded PLGA microparticles for intravaginal delivery. Abstract Background Intravaginal drug administration is the most promising strategy for treating vaginal infections to protect women's health, such as vulvovaginal candidiasis (VVC). However, conventional vaginal formulations in the clinic face challenges such as drug leakage and low ...
Yanyu Li +8 more
wiley +1 more source
Retrospective Cohort Study of Pregnancy Maternal Outcomes of Women With COVID-19 in King Salman Armed Forces Hospital, Tabuk, Kingdom of Saudi Arabia. [PDF]
Koja AW +3 more
europepmc +1 more source
The Dynamics of Neurofilament Light Chain in Spinal Muscular Atrophy
Objective Newborn screening (NBS) for spinal muscular atrophy (SMA) facilitates early diagnosis and treatment for affected individuals. However, fluid biomarkers that provide early insights into disease activity and outcomes in a neonatal cohort and those unable to access (due to reimbursement criteria) or deferring immediate treatment are lacking ...
Arlene D'Silva +13 more
wiley +1 more source
The Association of the COVID-19 Pandemic With Disparities in Maternal Outcomes. [PDF]
Glance LG +9 more
europepmc +1 more source
Severe maternal outcomes in 36 West African hospitals from Benin, Burkina Faso and Niger. [PDF]
Compaoré GD +10 more
europepmc +1 more source

