Results 31 to 40 of about 1,727,355 (121)

Hargai petugas PKU, barisan hadapan kita [PDF]

open access: yes, 2020
Kuantan, 9 April – Mendepani penularan wabak Covid-19 yang telah diisytiharkan sebagai pandemik oleh Pertubuhan Kesihatan Sedunia (WHO), Pusat Kesihatan Universiti (PKU) sentiasa bersiap siaga ‘memerangi’ penularan wabak tersebut di kampus ...
Siti Nurfarmy, Ibrahim
core   +1 more source

Re‐evaluation of salt of aspartame‐acesulfame (E 962) as food additive

open access: yesEFSA Journal, Volume 24, Issue 9, September 2026.
Abstract The present opinion deals with the re‐evaluation of salt of aspartame‐acesulfame (E 962) as a food additive. The Panel considered that upon ingestion, E 962 dissociates into aspartame and acesulfame ions which correspond to those of the authorised sweeteners aspartame (E 951) and acesulfame K (E 950). The Panel therefore assessed the safety of
EFSA Panel on Food Additives and Flavourings (FAF)   +34 more
wiley   +1 more source

One‐step generation of heritable mitochondrial DNA multiplex‐engineered rats using DddA‐derived cytosine base editor

open access: yesAnimal Models and Experimental Medicine, Volume 9, Issue 8, Page 1648-1660, August 2026.
We established that mixed DdCBE microinjection is an efficient, heritable, and precise strategy for generating multiplex mtDNA mutant rats. This advancement significantly expands the utility of DdCBEs for mitochondrial disease modeling, providing a robust platform for exploring the pathogenic mechanisms of complex mtDNA mutations and developing ...
Xu Zhang   +14 more
wiley   +1 more source

The PKU mouse project: its history, potential and implications

open access: yes, 1994
Click on the DOI link below to access the article (may not be free).To produce genetic-based animal models for the human disease phenylketonuria (PKU), we treated mice with the powerful germline mutagen ethylnitrosourea and screened the progeny of these ...
JD McDonald, McDonald, J. David
core   +1 more source

Cross Sectional Study of Prenatal Diagnosis Uptake Among Individuals With Genetic Conditions

open access: yesPrenatal Diagnosis, Volume 46, Issue 9, Page 1374-1384, August 2026.
ABSTRACT Objective Prenatal diagnostic genetic testing allows for early identification of significant fetal conditions and enables informed decision‐making regarding management options. The aim of this study was to assess prenatal testing practice among individuals with genetic conditions.
Ebunoluwa Ojo   +4 more
wiley   +1 more source

Food Poverty and Early Childhood Development Across Food Insecurity Levels in Brazil

open access: yesMaternal &Child Nutrition, Volume 22, Issue 3, July 2026.
ABSTRACT This cross‐sectional study investigated associations between food insecurity, food poverty, and early childhood development (ECD) among Brazilian children under 5 years of age, and explored whether the association between food poverty and ECD varied across food insecurity levels.
Micaela Rabelo Quadra   +6 more
wiley   +1 more source

Reproxalap ‐ A Novel Treatment Option for Allergic Conjunctivitis – A Comprehensive Narrative Review

open access: yesHealth Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background and Aims Allergic conjunctivitis is a prevalent, immune‐mediated hypersensitivity disorder of the ocular surface affecting 10%–20% of the global population. Current therapeutic options, while effective to some extent, are often limited by side effects and inconsistent efficacy.
Sanila Mughal   +7 more
wiley   +1 more source

Respect PKU staff, our frontliners [PDF]

open access: yes, 2020
Facing of the outbreak of the Covid-19 that has been declared a pandemic by the World Health Organization (WHO), the Center for Health (PKU), Universiti Malaysia Pahang (UMP) is always on alert to fight the spread of the outbreak in both university ...
UMP, PNC
core   +1 more source

Impact of pregnancy planning and preconceptual dietary training on metabolic control and offspring's outcome in phenylketonuria

open access: yes, 2022
To prevent maternal phenylketonuria (PKU) syndrome low phenylalanine concentrations (target range, 120–360 μmol/L) during pregnancy are recommended for women with PKU.
Rosenbaum-Fabian, Stefanie   +3 more
core   +1 more source

The 3‐Hit Metabolic Signaling Model for Autism Spectrum Disorder: A Summary

open access: yesAutism Research, Volume 19, Issue 5, May 2026.
ABSTRACT Autism spectrum disorder (ASD) is a highly heritable yet environmentally sensitive neurodevelopmental condition whose biological heterogeneity has resisted a unifying causal explanation for over 100 years. The 3‐hit metabolic signaling model proposes that ASD arises from abnormal persistence of an evolutionarily conserved stress‐response ...
Robert K. Naviaux
wiley   +1 more source

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