Results 41 to 50 of about 236,603 (296)

Noticing and helping the neglected child: A Review of the literature [PDF]

, 2010
This report presents findings from a systematic literature review examining the evidence on the extent to which practicioners are equpped to recoconise and respond to the indicators that a child's needs are likely to be or are being neglected, whatever ...
Barbour, M., Daniel, Brigid, Scott, J., Taylor, Julie   +3 more
core   +1 more source

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

Advanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao, Lifang Guo, Guochao Yang, Chaoli Huang, He Wang, Jian‐Jun Yang, Guiquan Chen, Yimin Hu   +7 more
wiley   +1 more source

Moving from maternal death review to surveillance and response: A paradigm shift

Indian Journal of Public Health, 2018
In the era of the sustainable development goals, India is committed to reduce its maternal mortality ratio to less than 70 per one lakh live births by 2030. An important strategy that was adopted in the Reproductive and Child Health Programme in 2010 was
Amrita Kansal, Suneela Garg, Malvika Sharma   +2 more
doaj   +1 more source

Maternal Preconception Antibiotic Exposure Disrupts Microbial Succession: A Transgenerational Risk for Offspring Gut Mucosal Immaturity and Colitis Susceptibility

Advanced Science, EarlyView.
This study reveals that maternal antibiotic exposure prior to conception disrupts intergenerational gut microbial succession. By enhancing maternal‐offspring microbial transmission, altering microbial developmental trajectories and increasing selective pressures during community assembly, these disturbances lead to persistent gut mucosal immaturity and
Yuzhu Chen, Ruqiao Duan, Cunzheng Zhang, Gaonan Li, XiaoLin Ji, Qi Zhang, Fei Pei, Kun Wang, Liping Duan   +8 more
wiley   +1 more source

Behaviour of Zoo-Housed Red Pandas (Ailurus fulgens): A Case-Study Testing the Behavioural Variety Index

Journal of Zoological and Botanical Gardens, 2022
The red panda is listed as “endangered” in the IUCN Red List of Threatened Species, due to the rapid population decline. Improving our knowledge on the red panda biology and ethology is necessary to enhance its husbandry and breeding in zoos. Behavioural
Caterina Spiezio, Mariangela Altamura, Janno Weerman, Barbara Regaiolli   +3 more
doaj   +1 more source

Addressing Inequity to Achieve the Maternal and Child Health Millennium Development Goals: Looking Beyond Averages. [PDF]

, 2012
Inequity in access to and use of child and maternal health interventions is impeding progress towards the maternal and child health Millennium Development Goals.
A Amouzou, AR Hosseinpoor, C Kurowski, CG Victora, CG Victora, D Gwatkin, D McIntyre, DR Gwatkin, E Zere, E Zere, Frida N Ngalesoni, FutureInstitute, George M Ruhago, H Masanja, I Rudan, J Boerma, J Bryce, L Say, M Fox, M Islam, M Munga, MC Hogan, MOHSW, MOHSW, N Daniels, N Kakwani, N Walker, NBS[Tanzania] and ORCMacro, Ole F Norheim, R Lozano, S Thomsen, T Mkandawire, TH Julian, UNICEF, W DeCormier-Plosky, W Winfrey, W.H.O   +36 more
core   +4 more sources

IGFBP5 Restores Endometrial Receptivity and Rescues Implantation Failure in Polycystic Ovary Syndrome

Advanced Science, EarlyView.
Impaired endometrial receptivity contributes to the poor pregnancy outcomes in women with PCOS. The authors found that decreased endometrial IL‐22 levels and disrupted STAT3‐IGFBP5 signaling pathway contributed to impaired endometrial receptivity. Supplementation with IL‐22 or IGFBP5 exerts a protective effect on implantation failure in PCOS‐like mice,
Baoying Liao, Chuyu Yun, Hongying Shan, Yuqian Wang, Xiunan Chen, Weisi Lian, Tianliu Peng, Min Zhao, Xunsi Qin, Kailun Hu, Ping Zhou, Yue Wang, Yanli Pang, Rong Li   +13 more
wiley   +1 more source

Digital Innovation in Midwifery Care: Development of the Nindya Suamiable Web to Improve Health Autonomy in Pregnant and Postpartum Women

Social Medicine
Maternal mortality continues to pose a significant challenge to public health, particularly in regions with limited geographical access and infrastructural constraints, such as East Kalimantan, Indonesia.
Nindya Mayangsari, Erwin Purwaningsih, Diana Mufidati   +2 more
doaj   +1 more source

Integrating Spatial Proteogenomics in Cancer Research

Advanced Science, EarlyView.
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang, Yang Wu, Feng Zhang, Parthiban Periasamy, Haiyue You, Denise Goh, Rachel Elizabeth Ann Fincham, Xin Ning, Danping Wu, Lu Liu, Ying Jiang, Zhiwen Qian, Joe Yeong, Yan Zhang   +13 more
wiley   +1 more source

Out-of-pocket expenditure for seeking health care for sick children younger than 5 years of age in Bangladesh: findings from cross-sectional surveys, 2009 and 2012

Journal of Health, Population and Nutrition, 2017
Background Bangladesh has committed to universal health coverage, and options to decrease household out-of-pocket expenditure (OPE) are being explored. Understanding the determinants of OPE is an essential step.
Tazeen Tahsina, Nazia Binte Ali, D.M. Emdadul Hoque, Tanvir M. Huda, Shumona Sharmin Salam, Mohammad Mehedi Hasan, Md Altaf Hossain, Ziaul Matin, Lianne Kuppen, Sarah P. Garnett, Shams El Arifeen   +10 more
doaj   +1 more source