Results 171 to 180 of about 9,810 (260)

Dysregulated proteolytic cascades in Netherton syndrome: from molecular pathology to preclinical drug testing

The Journal of Pathology, EarlyView.
Abstract Netherton syndrome (NS) is a rare, severe, and often life‐threatening disease for which current therapeutic approaches are limited and show variable effectiveness. NS is characterized by excessive epidermal desquamation that results in a highly defective epidermal barrier, constitutive skin inflammation, allergies, and hair abnormalities.
Eleni Zingkou, Evangelos Bisyris, Georgios Pampalakis, Georgia Sotiropoulou   +3 more
wiley   +1 more source

The narrow window of protection: protective efficacy of maternally derived antibodies against virulent classical swine fever virus in Japan. [PDF]

Vet Res
Fukai K, Nishi T, Ikezawa M, Kawaguchi R, Morioka K.   +4 more
europepmc   +1 more source

The Expanding Role of Gene Sequencing in Shaping Fetal Therapies: Clinical and Ethical Considerations

Prenatal Diagnosis, EarlyView.
ABSTRACT In utero interventions are transformative in addressing genetic and anatomic conditions during fetal development. Next generation sequencing enables early genetic testing, playing a pivotal role in prenatal decision‐making by supporting risk stratification, precise and timely diagnosis, which directly informs eligibility for fetal surgical and
Matthew A. Shear, Beltran Borges, Billie R. Lianoglou, Tony Lum, Emma Canepa, Jennifer L. Cohen, Julia E. H. Brown, Akos Herzeg   +7 more
wiley   +1 more source

Advancing Extracellular Vesicle Research: A Review of Systems Biology and Multiomics Perspectives

PROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound vesicles secreted by various cell types into the extracellular space and play a role in intercellular communication. Their molecular cargo varies depending on the cell of origin and its functional state.
Gloria Kemunto, Samaneh Ghadami, Kristen Dellinger   +2 more
wiley   +1 more source

Clinical assessment of transplacental transfer of maternal SARS-CoV-2 IgG antibodies against spike and nucleocapsid proteins: A chemiluminescence microparticle immunoassay study. [PDF]

PLoS One
Sharmin E, Khan AI, Ahmed SF.
europepmc   +1 more source

Arbuscular mycorrhizal fungal inoculation increases the bioavailability of zinc and iron in wheat grain

PLANTS, PEOPLE, PLANET, EarlyView.
Bread wheat is an important crop that supplies calories and nutrients to the global population. Enhancing the concentrations and bioavailability of essential micronutrients in wheat is crucial for human nutrition, and we investigated whether arbuscular mycorrhizal (AM) fungi can contribute to the biofortification of wheat.
Thi Diem Nguyen, Alexander A. T. Johnson, Enzo Lombi, Casey L. Doolette, Euan Smith, Stephanie J. Watts‐Williams   +5 more
wiley   +1 more source

Maternal-infant rotavirus-specific antibody kinetics to inform timing of vaccine boosting in Malawi: An observational study. [PDF]

PLoS Med
Mandolo J, Mulira L, Moyo M, Mvula M, Mtonga F, Henrion MYR, Wotcheni W, Cunliffe NA, Barnes KG, Jambo KC, Jere KC.   +10 more
europepmc   +1 more source

Hybrid Probiotic Hydrogel With Curcumin‐Loaded MnO2 Nanoparticles Enhances Diabetic Wound Healing Through Multimodal Microenvironmental Regulation

Rare Metals, EarlyView.
ABSTRACT Skin wound injuries are often accompanied by bacterial infections and severe inflammation. Especially, M1‐type macrophages at the wound site can trigger a cascade of inflammatory responses, mediating a vicious cycle of inflammation. Meanwhile, hypoxia further exacerbates vascular damage and constriction in the wound microenvironment, thereby ...
Xianfeng Wang, Yuwen Shangguan, Hao Nan, Lingze Chen, Chencheng Gu, Litao Yan, Huan Li   +6 more
wiley   +1 more source

Low maternal pertussis protection and quantified infant risk: supporting maternal Tdap vaccination in China. [PDF]

Front Immunol
Wang W, Zhang T, Sun X.
europepmc   +1 more source

Global Health Governance Cannot Keep Relying on the Development‐Goals Model to Effectively Address Health Inequalities Around the World

Sustainable Development, EarlyView.
ABSTRACT The Sustainable Development Goals (SDGs) are nearing their end in 2030, and it is highly unlikely that many of the SDGs would be met by the target date. This calls for the urgent need for an upgraded approach or a new strategy from the “development‐goals” model.
Funom Theophilus Makama
wiley   +1 more source