Results 51 to 60 of about 138,809 (268)

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Nouvelles perspectives dans la littérature brésilienne contemporaine : Vozes-Mulheres et Quantos filhos Natalina teve ? de Conceição Evaristo

Amerika, 2017
This article’s purpose is to analyze one the expression of a Brazilian contemporary feminism in Vozes-Mulheres et Quantos filhos Natalina teve? from Conceição Evaristo through the prism of gender and postcolonail studies.
Pauline Champagnat
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

The Stigma on “the Tigress-Cub”: Late-Victorian Psychiatric Genetics and Wilkie Collins’ The Legacy of Cain

Lea
This article explores the intersections of Victorian medicine and literature by examining medical treatises on hereditary psychosis and criminal instincts and Wilkie Collins’ The Legacy of Cain (1888).
Stefano Rossi
doaj   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Seniority in Midwifery in Tanzania

Nordic Journal of African Studies
Concepts of seniority and elderhood were important structuring elements in many societies of precolonial Africa and were connected with social status. This changed with the European colonization of Africa, and strongly affected traditional cultures of ...
Veronica Kimani, Ulrike Lindner
doaj   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Raising the Awareness of Employees at the Maternity Departments Regarding Compliance with Infection Control Precautions [PDF]

Helwan International Journal for Nursing Research and Practice
Background: Infections before, during labor and the puerperium are among the leading causes of maternal mortality and morbidity, so all employees are crucial in preventing and controlling hospital-acquired infections.
Suzan Mobarak, Neama Abd El Gawad, Shaimaa Mohamady   +2 more
doaj   +1 more source

Maternal sepsis

Seminars in Perinatology, 2018
Sepsis is a leading cause of maternal morbidity and mortality in developed and developing nations. Obstetric practitioners should be familiar with guidelines that promote the safe and expeditious recovery of those affected. This article will provide the reader with rational steps to aid in the recovery of such a patient.
openaire   +3 more sources