Results 171 to 180 of about 292,234 (313)

Maternity care bundle for UK women with multiple long-term health conditions: coproduction workshops. [PDF]

BMJ Open
Hanley S, McCann S, Singh M, Vowles Z, Lee SI, Plachcinski R, Nirantharakumar K, Black M, Locock L, Taylor B.   +9 more
europepmc   +1 more source

SLC2A3‐Mediated Lactate Metabolism Promotes Lung Cancer Bone Metastasis by Modulating P53 Lactylation and Immune Evasion

Advanced Science, EarlyView.
SLC2A3 derived lactate promotes metastasis through p53 lactylation at K120 and osteoclast differentiation. Pharmacological inhibition of SLC2A3 upregulates PD‐1 expression on CD8+ T cells via lactate induced p53 lactylation, which modulates immune evasion. ABSTRACT Bone metastasis is a devastating consequence of lung cancer.
Yi Ding, Yuying Tian, Wenjie Ren, Xianglin Hu, Mengjuan Li, Bei Liu, Chen chen, Yunhan Lu, Lei Li, Wangjun Yan, Kun Li   +10 more
wiley   +1 more source

Editorial Expression Of Concern: Maternal fat free mass during pregnancy is associated with birth weight

Reproductive Health
Yanxia Wang, Jie Mao, Wenling Wang, Jie Qiou, Lan Yang, Simin Chen   +5 more
doaj   +1 more source

Work-related musculoskeletal disorder among midwives, a threat for maternity care. [PDF]

PLoS One
Mohammed OY, Erlandsson K, Seyoum T, Hailemeskel S, Derseh L, Lindgren H.   +5 more
europepmc   +1 more source

NanoLoop: A Deep Learning Framework Leveraging Nanopore Sequencing for Chromatin Loop Prediction

Advanced Science, EarlyView.
Chromatin loops are central to gene regulation and 3D genome organization. Leveraging Nanopore sequencing's ability to jointly capture DNA sequence and methylation, we present NanoLoop, the first framework for genome‐wide chromatin loop prediction using Nanopore data.
Wenjie Huang, Li Tang, Matthew C. Hill, Yonghao Zhang, Jun Xie, Min Li   +5 more
wiley   +1 more source

An empirical study of integration models and mechanisms for maternity care in innovative vocational education. [PDF]

Sci Rep
Luo W.
europepmc   +1 more source

Macrophage TRIM21 Inhibition Ameliorates Murine Acute Pancreatitis via PHB2‐Mediated Mitochondrial Stabilization

Advanced Science, EarlyView.
Macrophage‐derived TRIM21 drives the progression of AP via ubiquitin‐proteasome‐mediated degradation of PHB2, leading to impaired PHB2‐mediated mitophagy. Therefore, accumulation of cytosolic mtDNA hyperactivates the cGAS‐STING signaling axis, thereby amplifying inflammatory cascades.
Yansong Xu, Yuansong Sun, Xin Zhou, Kai Song, Chunlin Yin, Zhaohua Wang, Fei Xie, He Li   +7 more
wiley   +1 more source

Longitudinal Association of Maternity Care Practices with Exclusive Breastfeeding in U.S. Hospitals, 2018-2022. [PDF]

Children (Basel)
Gosdin L, Marks KJ, Addo OY, O'Connor L, Awan S, Grossniklaus DA, Hamner HC.   +6 more
europepmc   +1 more source

Identification of A p300–SP1–BRD4 Transcriptional Axis as a Key Driver of AR Hyperactivation in Polycystic Ovarian Syndrome

Advanced Science, EarlyView.
This study reveals a pivotal epigenetic regulatory role for the histone acetyltransferase p300, demonstrating that its acetylation of histone 3 at lysine 18 and 27 (H3K18ac and H3K27ac), alongside the formation of the p300/BRD4/SP1 complex, drives AR activation and ovarian fibrosis in PCOS.
Zhengquan Zhu, Yihan Wang, Haiyun Chen, Xinye Yu, Tingyu Wang, Yajing Weng, Meihong Guo, Ying Huang, Gaojian Tao, Wangsen Cao, Yong Wang, Daojuan Wang   +11 more
wiley   +1 more source

Maternity Care Access and Infant Mortality.

JAMA Netw Open
Lucas R, Thames T, Chestnut JF, DeMaria AL, Stoneburner A.   +4 more
europepmc   +1 more source