Results 91 to 100 of about 283 (206)

Every contact counts: a call for inclusion of meaningful relational maternity care in low-income and middle-income countries

The Lancet Primary Care
Summary: Within maternity services, much emphasis has been placed on continuity of care and continuity of carer as key conduits for trusting relationships and positive experiences, which are essential for improved outcomes.
ProfPhD Tina Lavender, Idesi Chilinda, PhD, Livuka Nsemwa, MSc, Tracey A Mills, PhD   +3 more
doaj   +1 more source

scGEN: Leveraging an Adaptive Weighting Strategy for Challenging Cell Clustering in Single‐Cell RNA‐seq

Advanced Science, EarlyView.
scGEN combines attribute–structure encoding, adaptive hard‐sample weighting, and regularized zero‐inflated negative binomial loss to resolve ambiguous single‐cell states. In the developing human pituitary, refined annotations reveal Pre.Gonado cells at 7 weeks and previously obscured developmental communication networks.
Fang Huang, Dayu Hu, Yaqi Dai, Aoyi Geng, Renxiang Guan, Hao Quan, Brett A. McGregor, Zhihan Wang, Nadeem Khan, Hongsheng Zhang, Jinghua Zhang, Mingyang Xia, Xiaoqiong Gu, Di Che, Junguk Hur, Xiaoyu Cui, Kai Guo   +16 more
wiley   +1 more source

Leaving no one behind: the impact of disability and socioeconomic status on maternal continuum of care

BMC Public Health
To ensure that women with disabilities (WwD) have access to essential maternal health services, understanding their service utilization within the continuum of care (CoC) framework is vital. However, the influence of women's disability status on maternal CoC has not been fully explored.
Turi, Ebisa, Gold, Lisa, Le, Ha N.D, Mannan, Hasheem, Lau, Eric H.Y., Abimanyi-Ochom, Julie   +5 more
openaire   +2 more sources

A Metabolic‐Epigenetic Axis of AARS1/IGF2BP3‐K280 Lactylation Sustains Endometrial Cancer Stemness and Recurrence

Advanced Science, EarlyView.
Lactate‐driven endometrial cancer relapse is mediated by enzymatic protein modification. Elevated lactate levels activate AARS1, which catalyzes K280 lactylation of IGF2BP3, therefore stabilizing HMGA2 mRNA and promoting tumor stemness and recurrence.
Peng Jiang, Yunfeng Zheng, Chenfan Tian, Yuan Tu, Xiaoxia Chang, Jiaxin Yu, Hangkun Yu, Chunxia Gong, Jie Xiong, Philip N. Baker, Yong Fu, Chao Tong   +11 more
wiley   +1 more source

Examining the Effect of Maternity Cash Incentives Under Nepal’s Aama Program on the Continuum of Maternity Care: A Difference-in-Differences Analysis of NDHS 2011 to 2022

Inquiry: The Journal of Health Care Organization, Provision, and Financing
This study examines whether higher maternity cash incentives under Nepal’s Aama Program —intended to reduce household out-of-pocket (OOP) expenditures for delivery care—are associated with completion of the continuum of maternity care across Nepal’s ...
Poonam Rawat MPH, Jon M. Hussey PhD, Karar Zunaid Ahsan PhD   +2 more
doaj   +1 more source

SAV1 in Cooperation With FKBP52 Participates in Implantation

Advanced Science, EarlyView.
The MST‐SAV1 complex modulates FKBP52 phosphorylation to fine‐tune PR activity, ensuring timely uterine transition to receptivity under estrogen signaling for implantation. Stromal SAV1 scaffolds MST1/2‐mediated FKBP52 phosphorylation via noncanonical Hippo to promote PR activity.
Yuhan Shao, Yafang Lu, Zhaoyu Jia, Junxiang Ren, Ziyi Ge, Xinyu Liu, Hui Zhao, Zi‐Jiang Chen, Junhao Yan, Wei Wang, Jia Yuan   +10 more
wiley   +1 more source

Inequities in the continuum of maternal care in Mexico: trends before and after COVID-19

International Journal for Equity in Health
Despite progress in maternal health coverage in Mexico, inequities persist, particularly in postnatal care. The COVID-19 pandemic further widened these gaps, disproportionately affecting women with similar health needs but different socioeconomic conditions.
Edson Serván-Mori, Rocio Garcia-Diaz, Sergio Meneses-Navarro, Octavio Gómez-Dantés, Diego Cerecero-García, Arachu Castro, Rafael Lozano   +6 more
openaire   +3 more sources

Bio‐Memristor Based on Clinical Bile Samples: A Proof‐of‐Concept Pilot Study for Detection of Gallbladder Cancer

Advanced Science, EarlyView.
In this work, we present a bile‐based memristor hardware framework that enables direct, label‐free identification of cholelithiasis and gallbladder cancer at the device level. The Ag/bile/FTO memristor features stable resistive switching and disease‐specific electrical responses, providing a conceptual foundation for circuits and an integrated ERCP ...
Junming Zhu, Yiyin Rong, Bai Sun, Ziwen Sun, Yifan Wang, Xiaobin Ren, Zelin Cao, Kaikai Gao, Jiawei Yu, Zhenkun Wang, Haoxuan Ma, Jichun Guo, Kai Cao, Mengrun Kang, Songling Wang, Fenggang Ren, Yi Lv, Qiang Lu   +17 more
wiley   +1 more source

Developing Metal–Polyphenol Network‐Based Single‐Protein Particle Encapsulation System for Sustained Release of Whey Protein to Mitigate Sarcopenia

Advanced Science, EarlyView.
Sarcopenia has emerged as a major health challenge in the aging population. Developing a sustained‐release system for whey protein may enhance its effectiveness in mitigating sarcopenia. Herein, a novel “single‐protein particle encapsulation” (SPPE) system is developed to protect whey protein and control its release.
Yafei Zhang, Yuning Zhang, Yongjian Ai, Yao Lu, Heng Quan, Zhen Zhang, Yuqi Wang, Yujia Luo, Xiaoxu Zhang, Yingying Lin, Sijia Song, Huiyuan Guo   +11 more
wiley   +1 more source

Socioeconomic inequality in the completion of the continuum of care for maternal, newborn, and child health in Malawi

Frontiers in Reproductive Health
Background Despite improvements in maternal, newborn, and child health (MNCH) service coverage in Malawi, completion of the continuum of care (CoC) remains low and unequally distributed across socioeconomic groups. This study quantified socioeconomic inequality in MNCH CoC completion and its determinants.
Mwandama, Redson, Munthali, Spy
openaire   +2 more sources