Results 161 to 170 of about 576,794 (314)
Irish Maternity Indicator System National Report 2018
, 2019 This Irish Maternity Indicator System (IMIS) Interim Report shows data from 19 maternity hospitals/units from January through December 2018. It encompasses 33 multidisciplinary metrics across a range of domains, including demographics, deliveries ...
Office of the National Women and Infants Health Programme (NWIHP) +2 more
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Advanced Science, EarlyView.Disturbed flow promotes the formation of TRIM21‐rich biomolecular droplets, which concentrate TRIM21 and PTPN14 and facilitate their SPRY‐FERM interaction (illustrated by the TRIM21 D355‐PTPN14 R132 salt bridge). This condensate‐driven proximity enables TRIM21 to catalyze K48‐linked polyubiquitination of PTPN14 at lysine 956, leading to proteasome ...
Xue He +10 more
wiley +1 more source
NICE: A Two‐Step Non‐Invasive Framework for Embryo cfDNA Read Enrichment and Quality Assessment
Advanced Science, EarlyView.The non‐invasive NICE framework, built on an ensemble stacking machine learning model, prioritizes embryos by analyzing cell‐free DNA from spent culture medium. By integrating multimodal signals, including genomic and epigenetic profiles, this automated approach standardizes morphological assessment without human bias, paving the way for more precise ...
Xueya Zhou +6 more
wiley +1 more source
Work-related stress and intention to leave among midwives working in Swiss maternity hospitals - a cross-sectional study. [PDF]
BMC Health Serv Res, 2021 Peter KA +3 more
europepmc +1 more source
Advanced Science, EarlyView.IL‐1β upregulates the protein level of WTAP, which promotes the m6A modification of ACSL4 mRNA in an IGF2BP2‐dependent manner, thereby enhancing its stability. The increased ACSL4 drives lipid peroxidation, leading to lysosomal membrane permeabilization (LMP) and impaired mitophagy, which collectively accelerate intervertebral disc degeneration (IVDD).
Shu Jia +8 more
wiley +1 more source
Methodological challenges and solution strategies during implementation of a midwife-led multicenter randomized controlled trial (RCT) in maternity hospitals. [PDF]
BMC Med Res Methodol, 2021 Striebich S +4 more
europepmc +1 more source
American Women's Hospitals Report, 1923
, 1923 Dr. Mabel Elliott, a physician with the American Women’s Hospitals reports from Athens, Greece on the services provided to Turkish refugees from the city of Smyrna, following the burning of Smyrna in September ...
Elliott, Mabel Evelyn, b. 1881
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Advanced Science, EarlyView.Macrophage RSAD2 dually regulates CMPK2—the rate‐limiting enzyme for mitochondrial DNA synthesis—by suppressing its ubiquitination and promoting its phosphorylation via Csnk2a2 recruitment. This amplifies mtDNA production, which simultaneously activates a cGAS‐STING‐IRF3‐RSAD2 feedforward loop and the NLRP3 inflammasome, driving a self‐sustaining ...
Haomiao Yuan +16 more
wiley +1 more source
Barbara Stimson to American Women's Hospitals
, 1942 Part of letter from Barbara Stimson to American Women's Hospitals, sent by Julia Stimson to Esther ...
Stimson, Barbara B. (Barbara Bartlett), b. 1898
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Advanced Science, EarlyView.BNC2 exhibits context‐dependent opposing functions across multiple cancer types. This study reveals BNC2 as an oncogenic driver of melanoma proliferation and metastasis through transcriptional activation of PIK3CA. The natural compound TSN simultaneously degrades BNC2 and its oncogenic partner SMAD3 via CRBN‐dependent ubiquitination.
Hui Dai +7 more
wiley +1 more source