Results 131 to 140 of about 2,198,195 (286)

Breakdown in Maternal Protection: Drugs [PDF]

open access: yesProceedings of the Royal Society of Medicine, 1968
openaire   +2 more sources

ACSL4‐Dependent Lysosomal Lipid Peroxidation Links WTAP‐Mediated m6A Modification to Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
IL‐1β upregulates the protein level of WTAP, which promotes the m6A modification of ACSL4 mRNA in an IGF2BP2‐dependent manner, thereby enhancing its stability. The increased ACSL4 drives lipid peroxidation, leading to lysosomal membrane permeabilization (LMP) and impaired mitophagy, which collectively accelerate intervertebral disc degeneration (IVDD).
Shu Jia   +8 more
wiley   +1 more source

[Maternity protection-also during the corona crisis]. [PDF]

open access: yesMed Klin Intensivmed Notfmed, 2020
Michels G, Ochmann U, Cranen R.
europepmc   +1 more source

Breakdown in Maternal Protection: Infections [PDF]

open access: yesProceedings of the Royal Society of Medicine, 1968
openaire   +2 more sources

National Maternity Hospital, Holles Street, annual report 1998

open access: yes, 1999
This report outlines the main activities of the hospital during a year which saw the continuation of the sustained increase in activity in recent years. The number of mothers delivered was 7,817, an increase of 3.4% over 1997 and 25% since 1994.
National Maternity Hospital (NMH)
core  

Macrophage RSAD2 Couples mtDNA Synthesis With a Self‐Amplifying Inflammatory Circuit to Orchestrate Tissue Repair

open access: yesAdvanced Science, EarlyView.
Macrophage RSAD2 dually regulates CMPK2—the rate‐limiting enzyme for mitochondrial DNA synthesis—by suppressing its ubiquitination and promoting its phosphorylation via Csnk2a2 recruitment. This amplifies mtDNA production, which simultaneously activates a cGAS‐STING‐IRF3‐RSAD2 feedforward loop and the NLRP3 inflammasome, driving a self‐sustaining ...
Haomiao Yuan   +16 more
wiley   +1 more source

National Maternity Hospital, Holles Street annual report 1999

open access: yes, 2000
I have pleasure in presenting the report on the hospital for the twelve months ended 31st December 1999. This report outlines the main activities of the hospital during a year where the hospital had to decline routine obstetrical bookings from areas ...
National Maternity Hospital (NMH)
core  

Natural Product Toosendanin Suppresses the Malignant Development of Skin Melanoma by Targeting BNC2 for Degradation

open access: yesAdvanced Science, EarlyView.
BNC2 exhibits context‐dependent opposing functions across multiple cancer types. This study reveals BNC2 as an oncogenic driver of melanoma proliferation and metastasis through transcriptional activation of PIK3CA. The natural compound TSN simultaneously degrades BNC2 and its oncogenic partner SMAD3 via CRBN‐dependent ubiquitination.
Hui Dai   +7 more
wiley   +1 more source

Optimized Cas9‐Enriched Nanopore Sequencing and Analysis Workflow for Clinical Diagnosis of Repeat Expansion Disorders

open access: yesAdvanced Science, EarlyView.
An optimized Cas9‐enriched nanopore sequencing workflow, combined with STRiker, enables simultaneous analysis of disease‐associated STR loci from patient blood. The nCATS–STRiker workflow detects repeat expansions, de novo repeat motifs, interruption patterns, and methylation in a single assay, improving the genetic diagnosis of previously undiagnosed ...
Seungbok Lee   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy