Results 91 to 100 of about 217,621 (296)

Vitamin D Regulates Olfactory Function via Dual Transcriptional and mTOR‐Dependent Translational Control of Synaptic Proteins

Advanced Science, EarlyView.
Vitamin D (VitD) modulates olfactory function by remodeling dendrodendritic synapses in tufted cells through vitamin D receptor‐dependent transcriptional and translational mechanisms. VitD regulates synaptic protein translation partially via mTOR signaling.
Pengcheng Ren, Renhe Cao, Xiaoshan Ye, Wenbin Pang, Qingshang Bi, Meihui Huang, Qionglin Zhou, Dan Ye, Wei Xiang, Le Xiao   +9 more
wiley   +1 more source

NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease

Advanced Science, EarlyView.
NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang, Yongwoo Na, Hyeonjoo Im, Garam Yang, Seungseon Yang, Hyun Soo Shim, Chunggoo Kim, GyeungYun Kim, Hyeok Ju Park, Hee Young Kim, Seung Eun Lee, Wonwoong Lee, Yoon Ha, Sungho Park, Jieun Kim, Won‐Young Cho, Woong Sun, Jong‐Seo Kim, Junsang Yoo   +18 more
wiley   +1 more source

Reducing laboratory costs through rational testing in suspected pre-eclampsia

BMJ Open Quality, 2022
Adam Daniel Jakes, Marsha Cox, Simon Drane, Antoinette Johnson   +3 more
doaj   +1 more source

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

Advanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang, Emilie Derisoud, Denise Parreira, Nayere Taebnia, Paulo R. Jannig, Reza Zandi Shafagh, Allan Zhao, Congru Li, Macarena Ortiz, Manuel Alejandro Maliqueo, Elisabet Stener‐Victorin, Volker M. Lauschke, Qiaolin Deng   +12 more
wiley   +1 more source

Priorities and strategies for improving disabled women's access to maternity services when they are affected by domestic abuse:a multi-method study using concept maps [PDF]

, 2015
BACKGROUND: Domestic abuse is a significant public health issue. It occurs more frequently among disabled women than those without a disability and evidence suggests that a great deal of domestic abuse begins or worsens during pregnancy.
A Akyuz, A Lazenbatt, A Parys Van, AL Coker, Anne Lazenbatt, B Williams, BA Bailey, C Barranti, C Bradbury-Jones, C Bradbury-Jones, C Bradbury-Jones, C Cockram, C Thomas, CA Kopac, Caroline Bradbury-Jones, D Hassouneh-Phillips, D Salmon, D Sumilo, DG Rosen, E Rodriguez, E Slayter, E Smith, EH Bradley, EM Shadigian, F Bradley, Fiona Duncan, G Feder, G Hague, G Hague, G Lewis, J Coles, J Ritchie, J Taylor, JC Flanagan, Jenna P. Breckenridge, JL Jasinski, JM Spangaro, John Devaney, JP Breckenridge, Julie Taylor, L Bacchus, L Bacchus, L Robinson, L Rose, LE Saltzman, LM Howard, LR Chambliss, M Banks, M Carolan, M Kane, M Redshaw, MA Nosek, MA Rodriguez, MJ Renfrew, MR Silverman, N Montalvo-Liendo, P Hoope-Bender ten, PS Shah, R O’Reilly, S Peckover, SG Shields, Thilo Kroll, UPIAS: 1976, WHO, WHO, WHO   +65 more
core   +4 more sources

HRS Degradation‐Induced Nicotinamide Deficiency in Placental Extracellular Vesicles Triggers Preeclampsia by Disrupting Maternal‐Fetal Immune Homeostasis

Advanced Science, EarlyView.
This study shows that lower NAM levels in PE‐derived pEVs correlate with disease severity. NAM‐deficient pEVs reduce Th1 and Th17 inhibition, leading to PE‐like symptoms. NAM in pEVs inhibits Th1 via SIRT1 and Th17 via macrophages. Reduced NAM in PE‐EVs is due to decreased HRS expression in trophoblasts, resulting from elevated HSP27.
Haiyi Fei, Yuhan Lin, Xiu Liu, Xiaohong Zhu, Xiaowen Lu, Zhan Shi, Fan Jia, Shiqian Xu, Ling Fang, Lingling Jiang, Songying Zhang   +10 more
wiley   +1 more source

Analysis of out-of-pocket expenditure in utilization of maternity care services in urban slums of Rajkot City, Gujarat

Indian Journal of Community Medicine, 2018
Background: India contributes 20% global maternal deaths every year. An important reason of such maternal mortality is due to cost of maternity services which makes it in accessible to the poor. Knowledge of maternity-related expense and its determinants
Sandeep Sharma, Pramod B Verma, Ankit P Viramgami, Mayur C Vala, Kaushik K Lodhiya   +4 more
doaj   +1 more source

A Lung‐Immune Dual‐Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses

Advanced Science, EarlyView.
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng, Jing Sun, Chun Lu, Qian Yu, Yiyun He, Bingqing Wu, Deshan Ren, Shuai Ding, Jincun Zhao, Yan Li   +9 more
wiley   +1 more source

Maternity services. [PDF]

BMJ, 1969
  +7 more sources

Engagement Matters– Maternity Services

International Journal of Integrated Care, 2015
Sharon Slane, Dawn Sturrock
doaj   +3 more sources