Results 171 to 180 of about 2,938,367 (285)

siRNA Delivery via Cross‐Linked Gelatin Microparticles Enables Targeted Modulation of Osteogenic‐Vascular Cross‐Talk: An Advanced Human 3D in Vitro Test System for Therapeutic siRNA

Advanced Healthcare Materials, EarlyView.
Osteogenic‐angiogenic cross‐talk is a vital prerequisite for vascularized bone regeneration. In this study, we investigated the effects of siRNA‐mediated silencing of two inhibitory proteins, Chordin and WWP‐1, via CaP‐NP‐loaded gelatin microparticles in osteogenically differentiated microtissues.
Franziska Mitrach, Jonas Kubat, Stefan Simm, Alexandra H. Springwald, Burak Demir, Anton Liebezeit, Michael C. Hacker, Michaela Schulz‐Siegmund   +7 more
wiley   +1 more source

A Mathematical Analysis of a Biomechanical Model for an Innovative Spinal Decompression and Correction System for the Conservative Treatment of Scoliosis. [PDF]

Bioengineering (Basel)
Jie Y, Zhang M, Li M, Luo C, Dong A, Luo YY, Zheng P, Zhang X, Liu Z, Li J, Wong MS, Wang AY, Ma CZ, Zhang M.   +13 more
europepmc   +1 more source

Mathematical analysis of a two-strain tuberculosis model in Bangladesh. [PDF]

Sci Rep, 2022
Kuddus MA, McBryde ES, Adekunle AI, White LJ, Meehan MT.   +4 more
europepmc   +1 more source

Engineered ETS1‐Nanoconjugate Restores Immune Homeostasis through Dual Immune‐Vascular Modulation in Relapsing and Progressive Multiple Sclerosis

Advanced Healthcare Materials, EarlyView.
The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang, Si‐Bo Yang, Yan Luo, Xiao‐Di Sun, Bo‐Hao Chang, Da‐Qiang Zhou, Jun‐Jie Jiang, Ya‐Nan Li, Jie‐Hong Wu, Hui‐Juan Jin, Hang Yang, Hang Hu, Yi‐Fan Zhou, Bo Hu   +13 more
wiley   +1 more source

Natural language processing reveals network structure of pain communication in social media using discrete mathematical analysis. [PDF]

Sci Rep
Okui N, Horie S.
europepmc   +1 more source

Mathematical analysis for spatial distribution of vessels, mast cells and adipocytes in superficial fascia. [PDF]

Front Physiol, 2022
Dong Y, Zhang D, Cao Y, Zhang Y, Sun X, Chen T, Zhang Y, Xu G.   +7 more
europepmc   +1 more source

Mathematical Dispositions and Student Learning: A Metaphorical Analysis [PDF]

, 2012
Cai, Jinfa, Moyer, John, Nie, Bikai, Robison, Victoria, Wang, Ning   +4 more
core   +1 more source

Wound Geometry Determines Whether Aligned‐Fiber Scaffolds Accelerate or Impede Diabetic Wound Healing: A Biased Random Walk Analysis

Advanced Healthcare Materials, EarlyView.
Wound closure is governed by geometry‐orientation coupling: aligned fibers speed migration along their axis but hinder perpendicular advance. In vivo diabetic wound experiments with composition‐matched fibrin, combined with an anisotropic diffusion (biased random‐walk) model, quantify this trade‐off and generate a healing landscape.
Yin‐Yuan Huang, Xiangjun Peng, Yuxuan Huang, Kunkoo Kim, Chengli Li, Peilun Hu, Sean J. Wang, Rohan Avula, Chun‐Yi Yang, Pengchao Ma, Shuhui Yang, Shumeng Jiang, Guy M. Genin, Xiumei Wang   +13 more
wiley   +1 more source

Mathematical analysis and control optimization of soluble and insoluble water pollutants dispersion. [PDF]

Heliyon
Oludoun OY, Salawu SO, Adesanya SO, Abiodun OE.   +3 more
europepmc   +1 more source

Mathematical analysis of hybrid mediated blood flow in stenosis narrow arteries. [PDF]

Sci Rep, 2022
Hussain A, Sarwar L, Rehman A, Al Mdallal Q, Almaliki AH, El-Shafay AS.   +5 more
europepmc   +1 more source