Results 61 to 70 of about 30,357 (278)
Early‐stage health technology assessment of a curative gene therapy for multiple sclerosis
Aims Multiple sclerosis (MS) is associated with significant early morbidity, reduced life expectancy and substantial healthcare and societal costs. The primary objective of this study is to assess the early cost‐effectiveness potential of a novel gene therapy, IMMUTOL, for MS compared with current high‐efficacy treatment sequences.
Attila Imre, Balázs Nagy, Rok Hren
wiley +1 more source
Abstract Drawing on teacher agency as a conceptual framework, we explored the extent to which school teachers in secondary schools in England achieve agency in relation to teaching climate change and sustainability. This research provides a novel approach to understanding the relational and emergent qualities of teacher agency by bringing together ...
Nicola Walshe, Elizabeth A. C. Rushton
wiley +1 more source
On the Existence of Evolutionary Learning Equilibriums
The usual kinds of Fixed-Point Theorems formalized on the existence of competitive equilibrium that explain much of economic theory at the core of economics can operate only on bounded and closed sets with convex mappings. But these conditions are hardly
Masudul Alam Choudhury
doaj +1 more source
Towards a material‐dialogic theory of climate teacher education: A global North–South dialogue
Abstract This paper develops a novel theoretical stance for reimagining initial teacher education (ITE) through genuine North–South dialogue that challenges dominant Global North paradigms in teacher education. Drawing on collaborative inquiry between researchers from England and Chile, we synthesise material‐dialogic space theory (derived from Global ...
Lindsay Hetherington +1 more
wiley +1 more source
Contradictory Effects of Ethical Neutrality and Formalization of Economics
The article analyses the issues of ethical neutrality and excessive formalization in modern econo-mics, and their mutual influence. The author systematizes the contradictory effects of ethical neutrality and excessive formalization on the development of ...
Olga V. NIFAEVA
doaj +1 more source
Conceptualizing Circular Ecosystems: An Analysis of 45 Definitions
ABSTRACT The circular ecosystem concept is gaining prominence among academics and practitioners. However, critics claim the concept is used and understood differently by different actors. While conceptual plurality offers possibilities for broad interpretations and engagement, it can undermine the relevance of the concept as an analytical lens due to ...
Martin Geissdoerfer +2 more
wiley +1 more source
Circular Economy Platforms: A Systematic Review
ABSTRACT Digital platforms enable circular business models that can provide both economic and environmental benefits. However, the literature on platforms in the context of the circular economy has remained descriptive and fragmented across fields, posing challenges for synthesizing accumulated knowledge.
Outi Blackburn +3 more
wiley +1 more source
The Modified Rural Postman Problem in Vehicle Route Optimization
The submitted paper deals with designing routes of the vehicles, which provide the transport network services. We limit our focus to such tasks, where the priority is the edge service in the transport network and the initial problem is finding an ...
Petr Kozel +2 more
doaj +1 more source

