Results 241 to 250 of about 24,796,113 (356)

siRNA Delivery via Cross‐Linked Gelatin Microparticles Enables Targeted Modulation of Osteogenic‐Vascular Cross‐Talk: An Advanced Human 3D in Vitro Test System for Therapeutic siRNA

Advanced Healthcare Materials, EarlyView.
Osteogenic‐angiogenic cross‐talk is a vital prerequisite for vascularized bone regeneration. In this study, we investigated the effects of siRNA‐mediated silencing of two inhibitory proteins, Chordin and WWP‐1, via CaP‐NP‐loaded gelatin microparticles in osteogenically differentiated microtissues.
Franziska Mitrach, Jonas Kubat, Stefan Simm, Alexandra H. Springwald, Burak Demir, Anton Liebezeit, Michael C. Hacker, Michaela Schulz‐Siegmund   +7 more
wiley   +1 more source

Engineered ETS1‐Nanoconjugate Restores Immune Homeostasis through Dual Immune‐Vascular Modulation in Relapsing and Progressive Multiple Sclerosis

Advanced Healthcare Materials, EarlyView.
The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang, Si‐Bo Yang, Yan Luo, Xiao‐Di Sun, Bo‐Hao Chang, Da‐Qiang Zhou, Jun‐Jie Jiang, Ya‐Nan Li, Jie‐Hong Wu, Hui‐Juan Jin, Hang Yang, Hang Hu, Yi‐Fan Zhou, Bo Hu   +13 more
wiley   +1 more source

Phenotype structuring in collective cell migration: a tutorial of mathematical models and methods. [PDF]

J Math Biol
Lorenzi T, Painter KJ, Villa C.
europepmc   +1 more source

Zinc‐Containing Bioactive Glass Programs Macrophage Polarization through Extracellular Traps Regulation for Enhanced Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Zinc‐containing bioactive glass (ZnBG) promotes diabetic wound healing by regulating macrophage extracellular traps (METs). Specifically, ZnBG reduces oxidative stress and inhibits the PAD4 and NLRP3/caspase‐1/GSDMD signaling pathways, thereby suppressing MET formation.
RuiYang Sun, XueBo Wei, ZhuoYang Song, JunJun Luo, JingYi Ye, YinNan Zhang, LiFei Zhu, Jie Gao, Hongyu Zhang, Hong Zhu, Xin Wang, Ke Xu   +11 more
wiley   +1 more source

Predicting Survival in Bevacizumab-Treated Colorectal Cancer: Personalized Mathematical Models Based on Clinical and Angiogenic Biomarkers. [PDF]

Int J Mol Sci
Moisuc DC, Marinca MV, Gafton B, Constantinescu D, Cianga P, Pavel-Tanasa M.   +5 more
europepmc   +1 more source

Nonlocal Conduction in a Metawire

Advanced Materials, Volume 37, Issue 13, April 2, 2025.
A 1D metawire composed of twisted copper wires is designed and realized. This metamaterial exhibits pronounced effects of nonlocal electric conduction according to Ohm's law. The current at one location not only depends on the electric field at that location but also on other locations.
Julio Andrés Iglesias Martínez, Yi Chen, Ke Wang, Martin Wegener   +3 more
wiley   +1 more source

A Systematic Computational Framework for Practical Identifiability Analysis in Mathematical Models Arising from Biology. [PDF]

Adv Sci (Weinh)
Wang S, Hao W.
europepmc   +1 more source

Shapeshifting Liquid Metal Droplets for Soft Fluidic Machines

Advanced Materials, EarlyView.
This study presented a liquid metal shape shifting strategy which harnesses Lorentz force, surface tension and fluid instabilities to achieve autonomous fluidic power. By using a liquid metal droplet as a mobile current carrier, this strategy enables the development of low‐voltage, self‐oscillating pumps that outperform existing soft pumps.
Saba Firouznia, Christian Romero, Hemma Philamore, Andrew Conn, Martin Garrad, Jonathan Rossiter   +5 more
wiley   +1 more source

Mathematical models to characterize the early phase of the COVID-19 pandemic in New Mexico, USA. [PDF]

Math Biosci Eng
Vestrand A, González-Parra G.
europepmc   +1 more source

Mathematical Modeling

Computers & Mathematics with Applications, 1979
openaire   +1 more source