Results 201 to 210 of about 61,168 (309)

Integrating Human Intestinal Organoids into FDA'S New Approach Methodologies for Drug Discovery

Advanced Science, EarlyView.
Illustration summarizes how human intestinal organoids (HIOs) are becoming transformative in preclinical research. Preclinical drug discovery pipelines often rely on animal models for ADMET studies, even though interspecies ADME gaps, poor external validity, and high attrition rates are common.
Debarun Patra, Ibrahim M. Sayed, Souhrid Mukherjee, Honit Piplani, Aida Habtezion, Michael J. Rosen, Jospeh C. Wu   +6 more
wiley   +1 more source

Single-cell aging trajectories reveal a dynamic coupling between nuclear size and proteasome concentration. [PDF]

iScience
Mobaraki M, Deng C, Zheng J, Li H.
europepmc   +1 more source

Extraction of Line Drawing with Some Lenth From Line Drawing image by Gray-Scale Mathematical Morphology

, 1998
Weiqing Tong, Shoji Tatsumi, Eiji Shimizu   +2 more
openalex   +2 more sources

Outstanding 1200 °C Oxidation Resistance in a Novel Multi‐Principal Element Alloy via Lattice Distortion‐Induced Diffusion Suppression

Advanced Science, EarlyView.
The unique lamellar structure of the eutectic alloy promotes selective oxidation of Al initially, while lattice distortion‐induced diffusion suppression slows oxide growth during steady state. Combining these strategies, a Multi‐Principal Element Alloy with excellent oxidation resistance at 1200℃ was designed.
Xinyu Zhang, Weiyan Lv, Xinguang Wang, Chuanmin Jia, Yizhou Zhou, Keqiang Qiu, Jianqiang Wang   +6 more
wiley   +1 more source

Fabrication Process and Surface Morphology Prediction of Radial Straight Groove-Structured CBN Grinding Wheel by Laser Cladding. [PDF]

Materials (Basel)
Ma Z, Zhang W, Liu Q, Chen L, Zhang C, Liu C, Yu T, Wang Q.   +7 more
europepmc   +1 more source

Feature Extraction on Images through a Mathematical Morphological Operation Using Watershed

, 2013
G.S.Raman G.S.Raman
openalex   +1 more source

Smart Optogenetics for Real‐Time Automated Control of Cardiac Electrical Activity

Advanced Science, EarlyView.
We are able to stop dangerous heart‐rhythm spirals before they fully form. Within about 100 ms, it pinpoints the spiral's tiny central tip (≈0.9 mm) using light‐based sensing and machine learning, then shines targeted light to shut it down. This fast, precise, closed‐loop approach detects, targets, and terminates arrhythmias in real time.
Shanliang Deng, Niels Harlaar, Juan Zhang, Sven O. Dekker, Nina N. Kudryashova, Huiling Zhou, Cindy I. Bart, TianYi Jin, Georgy Derevyanko, Willem van Driel, Alexander V. Panfilov, René H. Poelma, Antoine A. F. de Vries, GuoQi Zhang, Tim De Coster, Daniël A. Pijnappels   +15 more
wiley   +1 more source

Enhancing cancer prognostics with group penalty models: a comparative study on radiomics feature selection in lung adenocarcinomas and meningiomas. [PDF]

Quant Imaging Med Surg
Kwon Y, Suh YJ, Park YW, Ahn SS, Han K, Ha MJ.   +5 more
europepmc   +1 more source

Fault detection using mathematical morphology and clustering

, 2000
Marcin Iwanowski
openalex   +1 more source

Random Projection Depth for Multivariate Mathematical Morphology

, 2012
Santiago Velasco-Forero, Jesús Angulo
openalex   +2 more sources