Results 161 to 170 of about 5,689,395 (335)

Covalent Binding of Dexamethasone to Polyimide Improves Biocompatibility of Neural Implantable Devices

Advanced Healthcare Materials, EarlyView.
The covalent binding of dexamethasone to the surface of polyimide represents the electrically inert part of implantable intraneural devices. This ensures a sustained release of the drug for 9 weeks. In vitro and in vivo tests confirm the reduction of the foreign body reactions and the improved biocompatibility of dexamethasone functionalized polyimide.
Giulia Turrin, Jose Crugeiras, Chiara Bisquoli, Davide Barboni, Martina Catani, Bruno Rodríguez‐Meana, Rita Boaretto, Michele Albicini, Stefano Caramori, Claudio Trapella, Thomas Stieglitz, Yara Baslan, Hanna Karlsson‐Fernberg, Fernanda L. Narvaez‐Chicaiza, Edoardo Marchini, Alberto Cavazzini, Ruben López‐Vales, Maria Asplund, Xavier Navarro, Stefano Carli   +19 more
wiley   +1 more source

Optimizing Drug Regimens in Cancer Chemotherapy by an Efficacy–Toxicity Mathematical Model [PDF]

, 2000
Athanassios Iliadis, Dominique Barbolosi
openalex   +1 more source

Erratum to "Making better decisions by applying mathematical optimization to cost accounting: An advanced approach to multi-level contribution margin accounting" [Heliyon 7 (2) (February 2021) e06096]. [PDF]

Heliyon, 2021
Gutiérrez M.
europepmc   +1 more source

Decoding Hydrogel Porosity: Advancing the Structural Analysis of Hydrogels for Biomedical Applications

Advanced Healthcare Materials, EarlyView.
Porosity governs transport mechanics in hydrogels, yet characterization in its native state remains challenging. This work harnesses particle tracking to uncover three‐dimensional pore geometric features in polyethylene glycol hydrogels. Measurements in the native state reveal pores characteristics are comparable to those obtained by cryogenic scanning
M. A. Kristine Tolentino, Eric Y. Du, Giulia Silvani, Elvis Pandzic, Kristopher A. Kilian, J. Justin Gooding   +5 more
wiley   +1 more source

Wiley‐Interscience Series in Discrete Mathematics and Optimization [PDF]

, 2000

openalex   +1 more source

Integration of Bioengineered Tools in Assisted Reproductive Technologies

Advanced Healthcare Materials, EarlyView.
A conceptual illustration depicting the collaboration between a medical professional (right) and a scientist (left). Their connection highlights the integration of scientific research and clinical practice. This representation underscores the role of emerging technologies in bridging fundamental research with applied reproductive healthcare.
Aslı Ak, Edith Coonen, Ron van Golde, Erik Vrij   +3 more
wiley   +1 more source

Imiquimod‐Loaded Phospholipid‐Free Small Unilamellar Vesicles Activate the Tumor Immune Microenvironment to Treat Liver Cancer and Liver Metastases

Advanced Healthcare Materials, EarlyView.
Imiquimod‐loaded nanoparticles (PFSUV‐IMQ) are found to decrease liver metastasis and liver tumor burden when administered intravenously. Flow cytometry, RNA‐seq and various experiments show that the anti‐tumor response is immune‐mediated by activating dendritic cells resulting in increased CD8 T cell infiltration and activity.
Vanessa Chan, Hsin‐Mei Lee, Haruka Takata, Sheng‐Liang Cheng, Yu‐Ting Yen, Lisa Pfeifer, Luke Rushton, Po‐Han Chao, Feng Zhao, Chun Yat Ong, Nojoud Al‐Fayez, Tatsuhiro Ishida, Yunching Chen, Shyh‐Dar Li   +13 more
wiley   +1 more source

Inhalability and Bioactivity of Spray‐Dried versus Pressurized Gas eXpanded Liquid Technology‐Processed Yeast Beta‐Glucan Microparticles for Anti‐Fibrotic Therapies

Advanced Healthcare Materials, EarlyView.
PGXTEC) liquid technology is utilized to develop highly respirable yeast beta‐glucan (YBG) microparticles for the treatment of pulmonary fibrosis. Compared to conventionally processed spray‐dried YBG, PGXTEC‐YBG exhibits greatly improved aerodynamic properties, enhanced pro‐fibrotic macrophage uptake, and effective downregulation of pro‐fibrotic ...
Nate Dowdall, Safaa Naiel, Quan Zhou, Pareesa Ali, Tamana Rubina Yousof, Emily Wong, Ricardo Couto, Byron Yépez, Bernhard Seifried, Paul Moquin, Rod Rhem, Myrna Dolovich, Martin Rainer Kolb, Kjetil Ask, Todd Hoare   +14 more
wiley   +1 more source

Using the NOABL flow model and mathematical optimization as a micrositing tool

, 1986
H.L. Wegley, James Barnard
openalex   +1 more source

Roll‐To‐Roll Production of Smart Dressings for Wound Monitoring

Advanced Healthcare Materials, EarlyView.
This study presents a roll‐to‐roll manufactured smart wound dressing capable of visually monitoring key wound biomarkers, including pH, humidity, and temperature. By integrating colorimetric sensors into flexible dressing substrates, the device offers real‐time, equipment‐free insights for infection detection and wound management, representing a ...
Ziheng Wang, Yujin Ahn, Semin Kwon, Tianhao Yu, Yumin Dai, Julia Walsh, Joo Hun Lee, Sang Mok Park, Seul Ah Lee, Murtuza Peerbhai, Chandan K. Sen, Hyowon Lee, Young L. Kim, Hyunjoon Kong, Chi Hwan Lee   +14 more
wiley   +1 more source