Multimodal Imaging Reveals Rapid Catecholamine Uptake and Release by Neutrophils
Advanced Science, EarlyView.We show that immune cells (neutrophils) synthesize, uptake, and store catecholamine neurotransmitters such as dopamine or adrenaline. They also release them in response to specific stimuli (serotonin), which we directly visualize using fluorescent nanosensors. We further demonstrate that catecholamines affect neutrophil functions (NETosis) and platelet
Jennifer Mohr +19 more
wiley +1 more source
, 2017 The series of String-Math conferences has developed into a central event on the interface between mathematics and physics related to string theory, quantum field theory and neighboring subjects.
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Amphoteric dissolution of two-dimensional polytriazine imide carbon nitrides in water. [PDF]
Philos Trans A Math Phys Eng Sci, 2023 Lisowska K +9 more
europepmc +1 more source
Dynamic Regulation of Endogenous Transcription Factor Hubs at Single‐Molecule Resolution
Advanced Science, EarlyView.This study combines single‐molecule microscopy and genome editing to characterize the dynamic behaviors of endogenous oncofusion transcription factor EWS::FLI1 in Ewing sarcoma cells. EWS::FLI1 forms neomorphic hubs that dynamically assemble and dissolve. The hubs are regulated during mitosis, by RNA, and by specific chemicals.
Shawn Yoshida +4 more
wiley +1 more source
100 years of math milestones: the Pi Mu epsilon centennial collection [PDF]
, 2019 This book is an outgrowth of a collection of 100 problems chosen to celebrate the 100th anniversary of the undergraduate math honor society Pi Mu Epsilon. Each chapter describes a problem or event, the progress made, and connections to entries from other
Garcia, Stephan Ramon, Miller, Steven J
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Decoding Spatial Heterogeneity and Multi‐Omics Regulation with Hierarchical Graph Learning
Advanced Science, EarlyView.ABSTRACT Recent advances in spatial multi‐omics technologies have enabled the simultaneous profiling of multiple molecular layers within the same tissue slice, providing unprecedented opportunities to investigate tissue spatial organization. However, most existing computational methods identify spatial domains in a purely data‐driven manner, rarely ...
Jiazhou Chen +6 more
wiley +1 more source
'Holey' niche! finding holes in niche hypervolumes using persistence homology. [PDF]
J Math Biol, 2022 Conceição P, Morimoto J.
europepmc +1 more source
Impedance of Nonelectroneutral Solid Electrolyte Interphases With Nanopores: A Theoretical Model
Advanced Science, EarlyView.Physical modeling reveals that often‐neglected non‐electroneutrality and nanopores in the solid‐electrolyte interphase (SEI) govern the impedance behavior. Under nonreactive conditions, the low‐frequency constant‐phase element (CPE) phenomenon can be attributed to the nonelectroneutral local conditions in the SEI.
Chenkun Li, Jun Huang
wiley +1 more source
Stratifications and foliations in phase portraits of gene network models. [PDF]
Vavilovskii Zhurnal Genet Selektsii, 2022 Golubyatnikov VP +3 more
europepmc +1 more source
Electrohydraulic Folding Ring Actuators for Radially Contracting Applications
Advanced Science, EarlyView.This work presents an Electrohydraulic Folding Ring Actuator that combines high‐performance electrohydraulic actuation with origami‐inspired folding geometry to achieve constricting radial actuation. This integration yields significant inner lumen constriction, alongside a gripping force capable of holding objects exceeding four times the actuator's ...
Gavril Yong En Tan +4 more
wiley +1 more source