Results 111 to 120 of about 1,178,507 (306)

Open research case study - Mathematics and Statistics

, 2022
Simon Kirby
openalex   +2 more sources

Hybrid Scaffolds Decouple Biochemical & Biophysical Regulation of Cell Phenotype

Advanced Healthcare Materials, EarlyView.
Replicating tissue‐specific extracellular matrix is crucial for understanding its role in disease. This work demonstrates independent control over stiffness, composition and 3D collagen architecture using hybrid scaffolds: patterned collagen perfused with defined hydrogels.
Xinyuan Song, Samantha C. Mitchell, Abbie N. Smart, William Hardiman, Daniel V. Bax, Ceri E. Staley, Catherine Probert, Pamela Collier, Marian Meakin, Alison A. Ritchie, Tania Mendonca, Amanda J. Wright, Victoria James, Anna M. Grabowska, Catherine L. R. Merry, Serena M. Best, Ruth E. Cameron, Jennifer C. Ashworth   +17 more
wiley   +1 more source

ANALYSIS OF THE OUTCOMES OF SURGICAL TREATMENT IN PATIENTS WITH BRONCHOPULMONARY CARCINOID TUMORS

Клінічна та профілактична медицина
Inroduction. Surgical resection of bronchopulmonary carcinoid tumors remains the primary treatment modality and provides good outcomes. There exists debate, however, about the optimal extent of resection for this disease.
Ivan Z. Vytvytskyi, Mamed M. Bagirov, Arkadiy H. Vysotskyy, Vadym H. Getman, Tеtiana A. Vysotska, Inna O. Honcharenko   +5 more
doaj   +1 more source

Peptomer Linkers Enable Kinetic Control over Co‐Delivery of Multiple Chemotherapeutics

Advanced Healthcare Materials, EarlyView.
A key challenge in combinatorial chemotherapeutic drug delivery is independent control over release kinetics, especially with drugs of similar size and structure. Here, peptoid substitutions to proteolytically degradable peptides enabled the design of fast and slow‐releasing drug linkers.
Carolyn M. Watkins, Samuel L. Hallam, Mariah J. Austin, Adrianne M. Rosales   +3 more
wiley   +1 more source

Improving the performance of Bayesian networks in non-ignorable missing data imputation

Kuwait Journal of Science, 2013
The issue of missing data may arise for researchers who deal with data gathering problems. Bayesian networks are one of the proposed methods that have been recently used in missing data imputation.
P. NILOOFAR, M. GANJALI, AND M.R. FARID ROHANI   +2 more
doaj  

Evaluation of Critical Thresholds for Surrounding Rock Stability in TBM Tunnels Utilizing Limit State Analysis

Buildings
The safety and stability of tunnel construction are paramount concerns in tunnel engineering. Traditionally, the assessment of tunnel stability involves evaluating whether tunnel displacement and deformation velocities exceed acceptable thresholds, using
Fawang Guo, Xiaoxuan Yu, Yipeng Shi, Chunyong Shen, Baoqiang Zhu, Hao Peng, Haizuo Zhou   +6 more
doaj   +1 more source

In Vivo Skin 3‐D Surface Reconstruction and Wrinkle Depth Estimation Using Handheld High Resolution Tactile Sensing

Advanced Healthcare Materials, EarlyView.
A compact handheld GelSight probe reconstructs in vivo 3‐D skin topography with micron‐level precision using a custom elastic gel and a learning‐based surface normal to height map pipeline. The device quantifies wrinkle depth across various body locations and detects changes in wrinkle depth following moisturizer application.
Akhil Padmanabha, Arpit Agarwal, Catherine Li, Austin Williams, Dinesh K. Patel, Sankalp Chopkar, Achu Wilson, Ahmet Ozkan, Wenzhen Yuan, Sonal Choudhary, Arash Mostaghimi, Zackory Erickson, Carmel Majidi   +12 more
wiley   +1 more source

Adequate Mathematical Models of the Cumulative Distribution Function of Order Statistics to Construct Accurate Tolerance Limits and Confidence Intervals of the Shortest Length or Equal Tails

, 2023
Nicholas A. Nechval, Gundars Bērziņš, Konstantin N. Nechval   +2 more
openalex   +1 more source

siRNA Delivery via Cross‐Linked Gelatin Microparticles Enables Targeted Modulation of Osteogenic‐Vascular Cross‐Talk: An Advanced Human 3D in Vitro Test System for Therapeutic siRNA

Advanced Healthcare Materials, EarlyView.
Osteogenic‐angiogenic cross‐talk is a vital prerequisite for vascularized bone regeneration. In this study, we investigated the effects of siRNA‐mediated silencing of two inhibitory proteins, Chordin and WWP‐1, via CaP‐NP‐loaded gelatin microparticles in osteogenically differentiated microtissues.
Franziska Mitrach, Jonas Kubat, Stefan Simm, Alexandra H. Springwald, Burak Demir, Anton Liebezeit, Michael C. Hacker, Michaela Schulz‐Siegmund   +7 more
wiley   +1 more source

Engineered ETS1‐Nanoconjugate Restores Immune Homeostasis through Dual Immune‐Vascular Modulation in Relapsing and Progressive Multiple Sclerosis

Advanced Healthcare Materials, EarlyView.
The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang, Si‐Bo Yang, Yan Luo, Xiao‐Di Sun, Bo‐Hao Chang, Da‐Qiang Zhou, Jun‐Jie Jiang, Ya‐Nan Li, Jie‐Hong Wu, Hui‐Juan Jin, Hang Yang, Hang Hu, Yi‐Fan Zhou, Bo Hu   +13 more
wiley   +1 more source