Results 221 to 230 of about 1,178,507 (306)

Research on the roundness error separation method for precision spindle based on harmonic wavelet de-noise and mathematical statistics method

, 2019
Shihai Zhang
openalex   +1 more source

Dual Targeting of Tau Kinases and Autophagy by Abemaciclib Independent of CDK4/6 Inhibition

Advanced Science, EarlyView.
Abemaciclib rescues cognitive function and attenuates tau pathology in Alzheimer's disease models, but not through its known cancer‐fighting mechanism. This study demonstrates that abemaciclib operates independently of CDK4/6 inhibition, instead directly targeting tau kinases CaMKII and GSK3β while simultaneously promoting autophagic clearance of ...
Jihui Han, June‐Hyun Jeong, Dongjoon Lee, Yujin Jung, Yujin Jin, Eun Sun Jung, Haeng Jun Kim, Woo Youn Kim, Chang‐Han Lee, Inhee Mook‐Jung   +9 more
wiley   +1 more source

Mathematical analysis of metronomic chemotherapy response in metastatic gastrointestinal cancer: identifying critical parameters from clinical data. [PDF]

Sci Rep
Manca ML, Michelangeli A, Bocci G, Orlandi P, Allegrini G, Kirken RA, Francia G, Georgiev V.   +7 more
europepmc   +1 more source

Comprehensive Survey: Mathematical Foundations of Deep Learning -Linear Algebra, Statistics, Gradients, and Tensor Operations [PDF]

Surya Rao Rayarao, Naga Donikena
openalex   +1 more source

OPTRACE: Optical Imaging–Guided Transplantation and Tracking of Cells in the Mouse Brain

Advanced Science, EarlyView.
OPTRACE establishes an optical, two‐step platform for intracerebral cell therapy. Transparent glass pipettes enable real‐time, image‐guided delivery, while multiplex genetic labeling with two‐photon and bioluminescence readouts supports longitudinal single‐cell tracking and host–graft dynamics.
Jinghui Wang, Honglin Tan, Colleen Russell, Mikolaj Walczak, Dawei Gao, Guanda Qiao, Xiaoxuan Fan, Chengyan Chu, Miroslaw Janowski, Piotr Walczak, Yajie Liang   +10 more
wiley   +1 more source

Mathematical Statistics [PDF]

, 1999
openaire   +1 more source

Convergent and Divergent Connectivity Patterns of the Arcuate Fasciculus in Macaques and Humans

Advanced Science, EarlyView.
This study employs viral‐based single‐neuron tracing and dMRI‐based whole‐brain tractography to investigate arcuate fasciculus (AF) trajectories in macaque monkeys, and compares with the human AF connectome using spectral embedding. Results demonstrate conserved AF topography spanning temporoparietal‐auditory‐frontal pathways across primates, with ...
Jiahao Huang, Ruifeng Li, Wenwen Yu, Anan Li, Xiangning Li, Mingchao Yan, Lei Xie, Qingrun Zeng, Xueyan Jia, Shuxin Wang, Ronghui Ju, Feng Chen, Qingming Luo, Hui Gong, Andrew Zalesky, Xiaoquan Yang, Yuanjing Feng, Zheng Wang   +17 more
wiley   +1 more source

Hybrid GA-SQP neural network frame for solving english language learning. [PDF]

Sci Rep
Abbasi AZ, Jaghdam IH, Aoudia M, Maatki C, Hassen W, Kolsi L.   +5 more
europepmc   +1 more source

Profiling of Integrin Isoforms on Lung‐Tropic Exosomes by Spectrally and Kinetically Multiplexed Single‐Molecule Imaging

Advanced Science, EarlyView.
A spectrally and kinetically multiplexed single‐molecule imaging method is developed, which achieved simultaneous imaging of 12 exosomal proteins at an unparalleled single‐copy resolution. It is found that co‐occurrence of α6 integrin and the pairing β counterpart on single exosomes is essential for lung targeting, providing valuable information for ...
Songlin Liu, Haixin Wang, Qin Shentu, Liang Yuan, Jiangshan Tie, Li Li, Rui Ai, Bochen Ma, Lubin Qi, Yifei Jiang, Xiaohong Fang   +10 more
wiley   +1 more source

Noninvasive Seizure Onset Zone Localization Using Janashia-Lagvilava Algorithm-Based Spectral Factorization in Granger Causality. [PDF]

Brain Sci
Kasradze S, Lomidze G, Ephremidze L, Gagoshidze T, Japaridze G, Alkhidze M, Jishkariani T, Dhamala M.   +7 more
europepmc   +1 more source