Results 251 to 260 of about 3,947,290 (367)

Resolving Artifacts in Voltage‐Clamp Experiments with Computational Modeling: An Application to Fast Sodium Current Recordings

Advanced Science, EarlyView.
Patch‐clamp experiments are fundamental to the measurement and understanding of ion currents that underlie physiological functions from neural activity to muscle contraction. Via a mathematical model of the experimental apparatus, this article highlights how artifact effects can be as large as some reported mutation and drug effects, and enables ...
Chon Lok Lei, Alexander P. Clark, Michael Clerx, Siyu Wei, Meye Bloothooft, Teun P. de Boer, David J. Christini, Trine Krogh‐Madsen, Gary R. Mirams   +8 more
wiley   +1 more source

Estimation of finite population mean in a complex survey sampling. [PDF]

PLoS One
Abbas M, Ahmed Shehzad M, Rabia M, Khurram H, Ijaz M.   +4 more
europepmc   +1 more source

Mathematical foundation workshop V-statistics of measurement

, 1975
W.L. Nicholson
openalex   +1 more source

Piezo1 Activation Improves NSCLC Liver Metastasis Immunotherapy by Overriding Matrix Stiffness‐Mediated Bimodal PD‐L1/CXCL10 Regulation

Advanced Science, EarlyView.
This study demonstrates that Piezo1 activation enhances FAK‐YAP‐mediated upregulation of PD‐L1 and CXCL10, thereby promoting an immunotherapy‐responsive tumor microenvironment in NSCLC. Cyclic stretch modulates the PD‐L1/CXCL10 response to ECM stiffness, reshaping their expression dynamics.
Tian Zhang, Yuan Li, Bo Cheng, Zhao Xu, Mengjie Liu, Jinteng Feng, Yixue Bai, Yang Yu, Panpan Jiang, Luying Geng, Feng Xu, Hui Guo   +11 more
wiley   +1 more source

Impact of Brownian motion on the optical soliton solutions for the three component nonlinear Schrödinger equation. [PDF]

Sci Rep
Baber MZ, Shahzad T, Mohammed WW, Ahmed N, Ceesay B, Yasin MW.   +5 more
europepmc   +1 more source

Next Steps in Statistics Education: Identifying Teacher Professional Development Needs for Teaching the Data Analysis Component of Primary Level Mathematics

, 2009
Aisling Leavy
openalex   +1 more source

Gompertz Law‐Based Biological Age (GOLD BioAge): A Simple and Practical Measurement of Biological Ageing to Capture Morbidity and Mortality Risks

Advanced Science, EarlyView.
The Gompertz law‐based biological age metric (GOLD BioAge) introduces interpretable convenient and interpretable calculations to capture mortality, disease, and frailty risks. Its applications to proteomics and metabolomics (ProtAge and MetAge) demonstrate clinical potential to enhance aging evaluation and prevent age‐related diseases.
Meng Hao, Hui Zhang, Jingyi Wu, Yaqi Huang, Xiangnan Li, Meijia Wang, Shuming Wang, Jiaofeng Wang, Jie Chen, Zhi jun Bao, Li Jin, Xiaofeng Wang, Zixin Hu, Shuai Jiang, Yi Li   +14 more
wiley   +1 more source

Stochastic gene expression in proliferating cells: Differing noise intensity in single-cell and population perspectives. [PDF]

PLoS Comput Biol
Zhang Z, Zabaikina I, Nieto C, Vahdat Z, Bokes P, Singh A.   +5 more
europepmc   +1 more source

APPROACHING THE BORDERLANDS OF STATISTICS AND MATHEMATICS IN THE CLASSROOM: QUALITATIVE ANALYSIS ENGENDERING AN UNEXPECTED JOURNEY

, 2010
Jane Watson, Erica Nathan
openalex   +2 more sources

Novel Cyano‐Artemisinin Dimer ZQJ29 Targets PARP1 to Induce Ferroptosis in Pancreatic Cancer Treatment

Advanced Science, EarlyView.
A novel artemisinin derivative dimer has been synthesized, and its significant potential as an anti‐cancer agent. The study indicated that ZQJ29 effectively inhibited the proliferation of pancreatic cancer cells in vitro and in vivo. Additionally, these investigations have unveiled ZQJ29 as a new potent PARP1 inhibitor, with the capability to induce ...
Jianping Chen, Lingyun Yue, Yanna Pan, Bingying Jiang, Junfeng Wan, Haixia Lin, Fujiang Guo, Huiyu Li, Yajuan Li, Qingjie Zhao   +9 more
wiley   +1 more source