Results 41 to 50 of about 376,980 (264)
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Al-Jabar, 2016 This study aims to determine whether the modification of learning models Gerlach and Ely through the integration of Islamic values can improve the ability of mathematical representation of learners.
Irda Yusnita +2 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Parental involvement and children’s mathematical outcomes
LUMATParental involvement is considered essential for children’s educational outcomes. Previous research has connected parental involvement to children’s mathematical achievement.
Arve Fiskerstrand +2 more
doaj +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
A FUZZY LOGIC APPROACH FOR MATHEMATICAL MODELING OF THE EXTRACTION PROCESS OF BIOACTIVE COMPOUNDS [PDF]
Journal of Engineering Science (Chişinău), 2019 he aim of the present study was to optimize the extraction process of bioactive compounds from berries and wastes from the agro-food industry (grape marc). Mathematical models of the extraction process of biologically active compounds based on algorithms
Aliona Ghendov-Moșanu +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
On applicability of mathematical scaling and normalization in applied problem solving
Advanced Engineering Research, 2018 Introduction. The applicability of mathematical scaling and normalization in solving various applied problems is analyzed. The best known formulas often used along the theoretical and experimental studies are considered.
A. I. Dolgov, D. V. Marshakov
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Mathematical model for exergy in the system NaCl-H2O [PDF]
Hemijska Industrija, 2004 In this work mathematical models for the exergy and relative enthalpy of the water solution of sodium-chloride and the pure crystalline sodium-chloride where derived.
Ninković Rozalija R. +2 more
doaj +1 more source