Results 31 to 40 of about 51,978 (203)

Multi‐Instably Mechanical Systems for Computing‐Storing Functions

open access: yesAdvanced Science, EarlyView.
Multi‐instably mechanical systems for the functions of scientific computing, logical operations, and data storage, i.e., solving fourth‐order ordinary differential equations (ODEs) by fourth‐order ODE solvers, realizing logical operations by digital logic gates, and stably storing data by mechanical memories.
Jiajun Wang   +3 more
wiley   +1 more source

Are physiological oscillations physiological?

open access: yesThe Journal of Physiology, EarlyView., 2023
Abstract figure legend Mechanisms and functions of physiological oscillations. Abstract Despite widespread and striking examples of physiological oscillations, their functional role is often unclear. Even glycolysis, the paradigm example of oscillatory biochemistry, has seen questions about its oscillatory function.
Lingyun (Ivy) Xiong, Alan Garfinkel
wiley   +1 more source

Mechanistic Modeling of Continuous Lyophilization for Biopharmaceutical Manufacturing

open access: yesAdvanced Science, EarlyView.
This article presents the first mechanistic model for continuous lyophilization (aka freeze drying). The model accurately describes the key phenomena and critical process parameters in continuous lyophilization, which can be used for process design, optimization, and control. Results from this work can drive the transition of (bio)pharmaceutical freeze
Prakitr Srisuma   +2 more
wiley   +1 more source

Backstepping Control of the One-Phase Stefan Problem

open access: yes, 2016
In this paper, a backstepping control of the one-phase Stefan Problem, which is a 1-D diffusion Partial Differential Equation (PDE) defined on a time varying spatial domain described by an ordinary differential equation (ODE), is studied. A new nonlinear
Diagne, Mamadou   +3 more
core   +1 more source

A systematic screening of neural network‐based hybrid models of adsorption in chromatography processes

open access: yesAIChE Journal, EarlyView.
Abstract In this study, various adsorption models using neural networks were developed and integrated into a mechanistic chromatography transport model, resulting in hybrid models. A systematic screening of 10 different hybrid model structures was performed to find the optimal balance between mechanistic and data‐driven components in modeling ...
Jesper Frandsen   +6 more
wiley   +1 more source

2D population balance modeling and ML‐based multi‐objective optimization for the crystallization process of resveratrol

open access: yesAIChE Journal, EarlyView.
Abstract Crystallization is critical in pharmaceutical manufacturing, influencing active pharmaceutical ingredient (API) purity and processability. This study models the cooling crystallization of resveratrol in a water‐ethanol solvent using a two‐dimensional population balance model (2D‐PBM). Experimental data from Focused Beam Reflectance Measurement
Álmos Orosz   +5 more
wiley   +1 more source

A stabilized radial basis-finite difference (RBF-FD) method with hybrid kernels

open access: yes, 2018
Recent developments have made it possible to overcome grid-based limitations of finite difference (FD) methods by adopting the kernel-based meshless framework using radial basis functions (RBFs). Such an approach provides a meshless implementation and is
Fasshauer, Gregory E   +3 more
core   +1 more source

Is Computing with Light All You Need? A Perspective on Codesign for Optical Artificial Intelligence and Scientific Computing

open access: yesAdvanced Intelligent Systems, EarlyView.
This perspective article considers what computations optical computing can and should enable. Focusing upon free‐space optical computing, it argues that a codesign approach whereby materials, devices, architectures, and algorithms are simultaneously optimized is needed.
Prasad P. Iyer   +6 more
wiley   +1 more source

Lambda and mu-symmetries

open access: yes, 2005
Lambda-symmetries of ODEs were introduced by Muriel and Romero, and discussed by C. Muriel in her talk at SPT2001. Here we provide a geometrical characterization of lambda-prolongations, and a generalization of these -- and of lambda-symmetries -- to ...
Gaeta, G.
core   +2 more sources

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