Results 31 to 40 of about 26,592,371 (260)
A Mathematical Problem for Security Analysis of Hash Functions and Pseudorandom Generators [PDF]
In this paper, we specify a class of mathematical problems, which we refer to as “Function Density Problems” (FDPs, in short), and point out novel connections of FDPs to the following two cryptographic topics; theoretical security evaluations of keyless hash functions (such as SHA-1), and constructions of provably secure pseudorandom generators (PRGs ...
Koji Nuida +4 more
openaire +3 more sources
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Making mathematics meaningful: Using student-initiated problems to situate mathematics [PDF]
Mathematics is everywhere-from the minute we open our eyes to check the alarm clock and calculate how many minutes extra we can afford to lie in bed, to measuring out our cereal for breakfast and estimating if we have enough petrol to make the 18 ...
Brough, Chris Jane, Calder, Nigel Stuart
core
Protocol for quantifying miRNA trafficking across the endosomal membrane
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Multifrequency induction hardening: a challenge for industrial mathematics
This book is a collection of papers presented at the Forum “The Impact of Applications on Mathematics” in October 2013. It describes an appropriate framework in which to highlight how real-world problems, over the centuries and today, have influenced and
Wakayama, Masato +10 more
core +1 more source
A Mathematical Modeling Framework for Analysis of Functional Clothing [PDF]
In the analysis and design of functional clothing systems, it is helpful to quantify the effects of a system on a wearer's physical performance capabilities. Toward this end, a clothing modeling framework for quantifying the mechanical interactions between a given clothing system design and a specific wearer performing defined physical tasks is ...
Xiaolin Man, Colby C. Swan, Ph.D
openaire +2 more sources
Heterotropic regulation and negative homotropic cooperativity
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova +9 more
wiley +1 more source
Digital technology in mathematics education: Why it works (or doesn't) [PDF]
The integration of digital technology confronts teachers, educators and researchers with many questions. What is the potential of ICT for learning and teaching, and which factors are decisive in making it work in the mathematics classroom? To investigate
Drijvers, Paul +3 more
core

