Results 41 to 50 of about 4,718 (211)

Computationally Evidence‐Grounded Sequence‐First Design of Peptide Binders

Advanced Science, EarlyView.
BOND‐PEP enables controllable, sequence‐first peptide binder design by grounding generation in binding evidence retrieved for each target. It uses topology‐conditioned message passing to integrate relevant peptide examples with the target protein sequence, forming a residue‐level representation that guides the generation of diverse, target‐specific ...
Wenze Ding
wiley   +1 more source

Inverse Design of Pre‐Strain via a Predictive Electromechanical Model for Enhanced Strain Sensing

Advanced Science, EarlyView.
An analytical electromechanical model rooted in microcrack evolution mechanics is globally calibrated from only eight pre‐strain datasets, enabling prediction of the complete sensing response at untested pre‐strain values within the calibrated design space (R2 > 0.99).
Jia‐Chen Shang, Rui Wang, Bo Lu, Ming‐Liang Song, Yu‐Yi Chen, Kuo Han, Xin‐Jie Feng, Bin Sun, Yao‐Guang Cao, Xiao‐Yu Yan, Shi‐Chun Yang   +10 more
wiley   +1 more source

The Polynomial Time Computation Engine ** A Mathematics Architecture via Geometric Topology Icosahedral Spectral Isomorphism

𝖳𝗁𝗂𝗌 𝗉𝖺𝗉𝖾𝗋 𝗌𝗂𝗍𝗎𝖺𝗍𝖾𝗌 𝗂𝗍𝗌𝖾𝗅𝖿 𝖺𝗍 𝗍𝗁𝖾 𝗂𝗇𝗍𝖾𝗋𝗌𝖾𝖼𝗍𝗂𝗈𝗇 𝗈𝖿 𝖼𝗈𝗆𝗉𝗎𝗍𝖺𝗍𝗂𝗈𝗇𝖺𝗅 𝖼𝗈𝗆𝗉𝗅𝖾𝗑𝗂𝗍𝗒 𝗍𝗁𝖾𝗈𝗋𝗒 𝖺𝗇𝖽 𝖽𝗂𝗌𝖼𝗋𝖾𝗍𝖾 𝗌𝗉𝖾𝖼𝗍𝗋𝖺𝗅 𝗀𝖾𝗈𝗆𝖾𝗍𝗋𝗒. 𝖶𝗁𝗂𝗅𝖾 𝗍𝗁𝖾 𝖠𝖪𝖲 𝖺𝗅𝗀𝗈𝗋𝗂𝗍𝗁𝗆 (𝟤𝟢𝟢𝟤) 𝖽𝖾𝖿𝗂𝗇𝗂𝗍𝗂𝗏𝖾𝗅𝗒 𝖾𝗌𝗍𝖺𝖻𝗅𝗂𝗌𝗁𝖾𝖽 𝗍𝗁𝖺𝗍 𝗉𝗋𝗂𝗆𝖺𝗅𝗂𝗍𝗒 𝗏𝖾𝗋𝗂𝖿𝗂𝖼𝖺𝗍𝗂𝗈𝗇 𝗋𝖾𝗌𝗂𝖽𝖾𝗌 𝗐𝗂𝗍𝗁𝗂𝗇 𝗍𝗁𝖾 𝖼𝗈𝗆𝗉𝗅𝖾𝗑𝗂𝗍𝗒 𝖼𝗅𝖺𝗌𝗌 𝖯, 𝗂𝗍𝗌 𝗉𝗈𝗅𝗒𝗇𝗈𝗆𝗂𝖺𝗅 𝖻𝗈𝗎𝗇𝖽 𝗋𝖾𝗆𝖺𝗂𝗇𝗌 𝖼𝗈𝗆𝗉𝗎𝗍𝖺𝗍𝗂𝗈𝗇𝖺𝗅𝗅𝗒 𝗉𝗋𝗈𝗁𝗂𝖻𝗂𝗍𝗂𝗏𝖾 𝖿𝗈𝗋 𝗁𝗂𝗀𝗁-𝗏𝖾𝗅𝗈𝖼𝗂𝗍𝗒 𝖼𝗋𝗒𝗉𝗍𝗈𝗀𝗋𝖺𝗉𝗁𝗂𝖼 𝗌𝖼𝖺𝗅𝗂𝗇𝗀.
openaire   +2 more sources

Programmable Topological Magnetic Textures in Above‐Room‐Temperature 2D Ferromagnet Fe3GaTe2

Advanced Science, EarlyView.
This work demonstrates the programmable generation and deterministic modulation of magnetic skyrmion bags with high‐order topological numbers in the above‐room‐temperature 2D ferromagnet Fe3GaTe2 (FGaT) via current‐pulse control. Furthermore, highly efficient electrical manipulation and current‐driven parallel motion of these high‐order topological ...
Hanqing Shi, Yilian Xi, Jingwei Zhang, Jiaqi Liu, Zhizhen Ren, Shilei Zhang, Weichang Hao, Haifeng Feng, Yi Du   +8 more
wiley   +1 more source

Information-Geometric and Topological Features of AI Behavioral Signatures: A 14-Module Mathematical Framework

Description of a 14-module mathematical pipeline spanning information theory, algebraic topology, dynamical systems, differential geometry, gauge theory, and category theory. Produces 272-dimensional feature vectors expanded to 1,543 dimensions. Achieves 0.958 AUC (GPT-4) on LLM behavioral drift detection.
openaire   +2 more sources

STWave: Fine‐Scale Spatial Structure Discovery in Microscopic‐Resolution Spatial Transcriptomics via Patchwise Wavelet Graphs

Advanced Science, EarlyView.
STWave transforms massive microscopic‐resolution spatial transcriptomics into interpretable fine‐scale tissue maps through patch‐wise inference, wavelet‐based multi‐scale encoding, and dual‐domain reconstruction. It reduces noise while preserving weak spatial signals, enabling efficient analysis of 6 40 000 spots of 2.47 GB GPU memory and revealing ...
Tao Jiang, Songming Zhang, Xiaofeng Chen, Xiongtao Xiao, Wenming Cao, Weikai Li, Tong Zhao, Bing Li, Xinyue Xu, Zhongshan Li   +9 more
wiley   +1 more source

Revealing the Underlying Mechanisms in Performance Enhancement of Shellular Lattice Electrodes During Anion Exchange Membrane Water Electrolysis Process

Advanced Science, EarlyView.
Micro laser powder bed fusion enables architected nickel shellular lattice gas diffusion layers for anion exchange membrane water electrolysis. Among regular open cell geometries, the Gyroid lattice promotes bubble release, convective reactant replenishment and continuous electron transport, delivering low overpotentials, enhanced charge transfer and ...
Tianxiao Niu, Rui Li, Xiao Chen, Deyong Sun, Tianyu Gao, Junhao Ding, Shuo Qu, Xu Song   +7 more
wiley   +1 more source

Mathematical and Physical Analysis of Geometric Genesis: Complete Technical Formalism on Mass Hierarchy, Topology and Geometry

Este informe presenta un análisis exhaustivo del formalismo matemático y físico que fundamenta la teoría de Génesis Geométrica, con enfoque particular en la derivación cuantitativa de la jerarquía de masas y propiedades de partículas elementales. Como cuarto componente de un ecosistema teórico coherente, este trabajo provee el rigor matemático técnico ...
openaire   +1 more source

Atmospheric Water Harvesting Through Polymer Hydrogel Sorbents: Materials Chemistry, Design Strategies, and Applications

Advanced Science, EarlyView.
Polymer‐based hydrogels have emerged as promising materials for atmospheric water harvesting (AWH) due to their high water affinity, tunable network structure, and excellent moisture adsorption‐desorption performance. Functional hydrogel systems enable efficient water capture and controlled release under low‐energy conditions, offering a sustainable ...
Swagata Datta, Sushmit Sen, Nilanjan Dey, Amrita Chatterjee, Ananya Sadhu, Sudipta Sarkar, Pradip K. Maji   +6 more
wiley   +1 more source

Decoding Viral Transmission Dynamics in Structured Populations Using a Microfluidic Herd‐Immunity‐on‐a‐Chip Platform

Advanced Science, EarlyView.
A microfluidic Herd‐Immunity‐on‐a‐Chip experimentally recreates structured contact networks to quantify viral transmission dynamics. By controlling susceptible, infected, and non‐susceptible populations, the platform reveals how contact topology governs the reproduction number, outbreak propagation, herd‐immunity–like behavior, and intervention ...
Jiande Zhang, Narina Jung, Min‐Hyeok Kim, Wanyoung Lim, Zhenzhong Chen, Byung Mook Weon, Sungsu Park   +6 more
wiley   +1 more source