Results 121 to 130 of about 1,612,043 (238)

Conditional Overexpression of Serpine2 Promotes Hair Cell Regeneration from Lgr5+ Progenitors in the Neonatal Mouse Cochlea

open access: yesAdvanced Science, EarlyView.
This study indicates that Serpine2 plays a pivotal role in hair cell (HC) regeneration from Lgr5+ progenitors in the neonatal mouse cochlea. Conditional overexpression of Serpine2 in cochlear Lgr5+ progenitors results in a significantly increased number of ectopic HCs, particularly ectopic inner HCs, and these HCs are likely derived from Lgr5 ...
Hairong Xiao   +14 more
wiley   +1 more source

Analyzing the neural wave structures in the field of neuroscience. [PDF]

open access: yesSci Rep
Younas U   +4 more
europepmc   +1 more source

Multiscale Dissection of Spatial Heterogeneity by Integrating Multi‐Slice Spatial and Single‐Cell Transcriptomics

open access: yesAdvanced Science, EarlyView.
Integrating multiple spatial transcriptomics datasets can provide a more comprehensive understanding of tissue structure and cellular heterogeneity. However, batch effects between different slices as well as between spatial transcriptomics and single‐cell reference data bring a great challenge for the integrative analysis.
Yuqi Chen   +4 more
wiley   +1 more source

Confinement by Liquid‐Liquid Interface Replicates In Vivo Neutrophil Deformations and Elicits Bleb‐Based Migration

open access: yesAdvanced Science, EarlyView.
Leukocytes sense mechanical cues provided by surrounding cells to regulate motility. Replicating the confining pressures applied by soft, elastic tissues in vitro is challenging. Here, the use of liquid‐liquid interfaces is introduced to model forces exerted by surrounding cells. Confining pressures are tunable by controlling interfacial curvature, and
Jonathan H. Schrope   +13 more
wiley   +1 more source

The Semi‐Natural Climate Chambers across Latitudes: A Broadly Applicable Husbandry and Experimental System for Terrestrial Ectotherms under Climate Change

open access: yesAdvanced Science, EarlyView.
Assessing species' vulnerabilities across geographical gradients is essential for biodiversity conservation under climate change. To address this challenge, the semi‐natural climate chamber across latitudes (SCCAL) is developed, a validated system capable of simulating thermal environments for ecological experiments without reliance on water or ...
Bao‐Jun Sun   +15 more
wiley   +1 more source

Broadband Acoustic Purcell Effect from Collective Bound States in the Continuum

open access: yesAdvanced Science, EarlyView.
This study introduces a novel six‐cavity system that utilizes collective quasibound states in the continuum (QBICs) to achieve a broadband acoustic Purcell effect. By strongly coupling five QBICs with an acoustic source within the introduced system, the research demonstrates a significant enhancement in sound emission from 625 to 900 Hz, paving the way
Sibo Huang   +6 more
wiley   +1 more source

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