Results 191 to 200 of about 961,565 (270)

Acidosis Forces Fatty Acid Uptake and Metabolism in Cancer Cells Regardless of Genotype

open access: yesAdvanced Science, EarlyView.
This study demonstrates that biological acidosis, commonly observed in tumors and ischemic conditions, actively promotes the protonation of fatty acids, thereby facilitating the uptake of their neutral forms. Consequently, the preference for lipid metabolism in acid‐exposed cells does not arise from genetic reprogramming that prioritizes lipids as the ...
Sébastien Ibanez   +20 more
wiley   +1 more source

Magnetic Field‐Driven Catalysis: Revealing Enhanced Oxygen Reactions in Li‐O2 Batteries Using Tailored Magnetic Nanocatalysts

open access: yesAdvanced Science, EarlyView.
A series of Mn‐Co‐Fe oxides with different saturated magnetization (Ms) are prepared to evaluate the enhancement catalytic properties of magnetic catalysts on Li‐O2 batteries (LOBs). A deep understanding of the intricate relationship between the magnetism of electrocatalysts and the corresponding performance of LOBs under the influence of magnetic ...
Yimin Chen   +9 more
wiley   +1 more source

Towards Nonlinearity: The <i>p</i>-Regularity Theory. [PDF]

open access: yesEntropy (Basel)
Bednarczuk E   +4 more
europepmc   +1 more source

Identifying Tipping Points during Healthy Brain Aging through Single‐Nucleus Transcriptomic Analysis

open access: yesAdvanced Science, EarlyView.
This study applies single‐nucleus transcriptomics and systems dynamics to uncover nonlinear aging patterns in healthy human brains. By introducing dynamic network biomarker theory, the authors identify a critical tipping point at ages 56–60 during aging, and highlight glial instability as a key mediator.
Peiru Wu   +9 more
wiley   +1 more source

MGPT: A Multi‐task Graph Prompt Learning Framework for Drug Discovery

open access: yesAdvanced Science, EarlyView.
MGPT is a unified multi‐task graph prompt learning model providing generalizable and robust graph representations for few‐shot drug association prediction. MGPT demonstrates the ability of seamless task switching and outperforms competitive approaches in few‐shot scenarios.
Yang Li   +4 more
wiley   +1 more source

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