Results 101 to 110 of about 3,906,906 (309)

Distributed Temporal Coding of Visual Memory Categories in Human Hippocampal Neurons Revealed by an Interpretable Decoding Model

open access: yesAdvanced Science, EarlyView.
This study examines how the human hippocampus encodes visual memory categories. By decoding spiking activity from CA3 and CA1 neurons using an interpretable model, it reveals that category‐specific representations emerge from distributed temporal coding.
Xiwei She   +17 more
wiley   +1 more source

PRO‐LDM: A Conditional Latent Diffusion Model for Protein Sequence Design and Functional Optimization

open access: yesAdvanced Science, EarlyView.
PRO‐LDM is a modular latent diffusion framework that learns hierarchical biological representations to enable efficient and high‐fidelity protein design. PRO‐LDM can design species that resemble natural sequences with enhanced diversity or optimize protein functions.
Sitao Zhang   +15 more
wiley   +1 more source

A Replicable and Generalizable Neuroimaging‐Based Indicator of Pain Sensitivity Across Individuals

open access: yesAdvanced Science, EarlyView.
Humans differ in their sensitivity to pain. With six large and diverse fMRI datasets (total N = 1046), this study finds that such individual differences in pain sensitivity can be tracked by fMRI responses to painful stimuli. A highly generalizable machine learning model is further built to predict pain sensitivity across all datasets and analgesic ...
Li‐Bo Zhang   +7 more
wiley   +1 more source

An Introduction to Mathematical Probability.

open access: yesJournal of the Royal Statistical Society, 1925
A. Z., J. L. Coolidge
openaire   +4 more sources

Smart Health Evaluation for Lithium‐Ion Battery With Super‐Short‐Segment Charging

open access: yesAdvanced Science, EarlyView.
This study proposes a health feature extraction method integrating degradation mechanism‐guided scale‐invariant feature transform with machine learning for lithium‐ion batteries. Validated across 87 commercial cells with diverse chemistries and formats, it achieves 1.97% RMSE in capacity estimation using only 10% charging segments. The approach enables
Qinghua Li   +6 more
wiley   +1 more source

A Systematic Computational Framework for Practical Identifiability Analysis in Mathematical Models Arising from Biology

open access: yesAdvanced Science, EarlyView.
A systematic computational framework is developed for practical identifiability analysis in biological models. The framework establishes a rigorous definition, introduces efficient coordinate‐based identifiability metrics, and proposes novel regularization strategies.
Shun Wang, Wenrui Hao
wiley   +1 more source

ChromInSight: Revealing DNA Double‐Strand Breaks Through Chromatin Structural Insights With an Interpretable Graph Neural Network Framework

open access: yesAdvanced Science, EarlyView.
DSBs are the most critical genomic lesions. Using the ChromInSight framework, It is revealed that 3D chromatin structure, rather than linear distance, shapes cluster‐scene between hub‐Nodes and DSB loci. The “spatial isolation–damage containment” hypothesis is proposed to illustrate how the genome responds to genomic damage and offer a powerful tool ...
Kang Xu   +9 more
wiley   +1 more source

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