Results 141 to 150 of about 2,386,799 (249)

The Interplay of Curvature, Geometry, and Topology Shapes Tissue Organisation in Epithelial Shells

open access: yesAdvanced Science, EarlyView.
Purely geometric 3D Voronoi models predict the organisation of epithelial shells. The interplay of curvature, geometry, and topology enriches the number of pentagons in shells with lower number of cells. Small MDCK cysts and Mouse embryos match the top polygonal configurations in a compactness‐based ranking derived from the Voronoi model. In conclusion,
Laura Morato   +9 more
wiley   +1 more source

Similarity‐Enhanced Representation Learning of Non‐Canonical Amino Acids for Therapeutic Peptide Modeling

open access: yesAdvanced Science, EarlyView.
Non‐canonical amino acids (ncAAs) enhance peptide therapeutics but remain difficult to model computationally. SinCAA, a similarity‐enhanced pretraining framework, jointly optimizes contrastive learning guided by a novel conformational similarity metric with masked node reconstruction, capturing both functional relationships and chemical identity of ...
Chencheng Xu   +8 more
wiley   +1 more source

An Introduction to Mathematical Probability.

open access: yesJournal of the Royal Statistical Society, 1925
A. Z., J. L. Coolidge
openaire   +2 more sources

MethyAnno: An Interpretable Automated Annotation Method Leveraging Multi‐Scale Information and Metric Learning Framework for scDNAm Data

open access: yesAdvanced Science, EarlyView.
MethyAnno enables robust and interpretable annotation of single‐cell DNA methylation data by integrating multi‐scale epigenetic information, bidirectional cross‐attention, and prototype‐based metric learning. The framework resolves rare and novel cell types across datasets while revealing cell‐type‐specific epigenetic signatures associated with disease
Yuhang Jia   +4 more
wiley   +1 more source

Mathematical skills in deaf and hard-of-hearing children: A systematic review. [PDF]

open access: yesPLoS One
Laria C   +9 more
europepmc   +1 more source

A Multi‐Scale Computational Framework for Evaluating Wireless Neuromodulation Feasibility via Magnetoelectric Nanoparticles

open access: yesAdvanced Science, EarlyView.
A multiscale computational framework links single‐nanoparticle magnetoelectric behavior to tissue‐level electric field distributions, integrating experimental data from nanoparticle characterization and in vitro stimulation setups. Applied to a cortical slice configuration, the framework predicts optimal MENP concentrations and stimulation parameters ...
Marta Bonato   +10 more
wiley   +1 more source

Multiscale modelling of birth-death processes. [PDF]

open access: yesJ Math Biol
Kimpson T   +3 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy