Results 131 to 140 of about 3,906,906 (309)

Targeting ROCK2 to Restore Epileptic Synaptic Networks via Mitophagy Activation: Insights from Translational Imaging of SV2A In Vivo

open access: yesAdvanced Science, EarlyView.
By integrating synaptic vesicle glycoprotein 2A PET imaging and transcriptomics, this study identifies Rho‐associated protein kinase 2 (ROCK2) as a critical regulator of synaptic network dysfunction in temporal lobe epilepsy. Pharmacological ROCK2 inhibition restores synaptic density and enhances mitophagy, thereby reducing seizures and neuronal damage.
Ling Xiao   +14 more
wiley   +1 more source

Enhancing Spatial Transcriptomics via Spatially Constrained Matrix Decomposition with EDGES

open access: yesAdvanced Science, EarlyView.
Imaging‐based spatial transcriptomics technologies are currently limited by their restricted gene detection capacity and low measurement accuracy. Moreover, the insufficient integration of spatial context and single‐cell reference data poses a significant challenge for comprehensive data analysis.
Jinyue Zhao   +5 more
wiley   +1 more source

Implementation of ICT using Hawgent dynamic mathematics software to teach probability

open access: gold, 2021
Tommy Tanu Wijaya   +5 more
openalex   +1 more source

Enabling High‐Performance Electrode Materials for Potassium‐Ion Batteries: Ionic Transport, Size and Electro–Chemo–Mechanical Effects

open access: yesAdvanced Science, EarlyView.
Potassium‐ion battery is a promising candidate for large‐scale energy storage applications. In this review, transport properties, size effects, and electro–chemo–mechanical properties of electrodes are systematically summarized in order to achieve the rational design and controlled synthesis of potassium electrodes.
Changbao Zhu, Yanpeng Fu, Yong Yang
wiley   +1 more source

Connecting Statistics, Probability, Algebra and Discrete Mathematics

open access: green, 2021
Fernando López-Blázquez   +3 more
openalex   +2 more sources

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