Results 191 to 200 of about 3,906,906 (309)

Model‐based fault diagnosis in closed‐loop safety‐critical chemical reactors: An experimental study

open access: yesAIChE Journal, EarlyView.
Abstract This experimental study investigates fault detection and estimation in a continuous stirred‐tank reactor (CSTR) system under closed‐loop feedback control, including an analysis of different manipulative inputs for temperature regulation. A novel fault diagnosis approach is proposed, combining residual signal analysis and T2 statistic for real ...
Pu Du, Benjamin Wilhite, Costas Kravaris
wiley   +1 more source

Modeling heterogeneity in large‐scale bioreactors using the method of moments with a truncated normal distribution

open access: yesAIChE Journal, EarlyView.
ABSTRACT Large‐scale bioreactors in industrial bioprocesses pose challenges due to extracellular concentration gradients and intracellular heterogeneity. This study introduces a novel approach integrating the method of moments with truncated normal distributions (MM‐TND) to model intracellular heterogeneity while maintaining computational feasibility ...
Ittisak Promma   +3 more
wiley   +1 more source

Predicting both thermodynamic and kinetic properties of crystallizing molecules via transformer‐based language model

open access: yesAIChE Journal, EarlyView.
Abstract Crystallization is pivotal in the chemical and pharmaceutical industry, affecting particle stability, and drug release. Crystal size distribution (CSD), a critical attribute of the final dosage form, is determined by the molecular structure of the crystallizing entity.
Silabrata Pahari   +3 more
wiley   +1 more source

Mapping uncertainty using differentiable programming

open access: yesAIChE Journal, EarlyView.
Abstract Uncertainty quantification (UQ) and propagation is a ubiquitous challenge in science, permeating our field in a general fashion, and its importance cannot be overstated. Recently, the commoditization of differentiable programming, motivated by the development of machine learning, has allowed easier access to tools for evaluating derivatives of
Victor Alves   +3 more
wiley   +1 more source

A stochastic programming framework for Nash bargaining in oligopolistic industrial gas markets with customer contracts

open access: yesAIChE Journal, EarlyView.
Abstract Mature industries, such as the industrial gases sector, often evolve into oligopolistic markets, which can amplify their susceptibility to market uncertainties. In this work, we propose a two‐stage stochastic Nash bargaining in industrial gases market oligopolies, accounting for electricity price and demand uncertainties.
Asimina Marousi   +3 more
wiley   +1 more source

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