Results 121 to 130 of about 609,384 (298)

Upper Limb Motor Function Rehabilitation System Leveraging Pressure‐Sensitive Intent Recognition

open access: yesAdvanced Science, EarlyView.
A novel upper limb rehabilitation system for stroke patients combines liquid metal elastomer sensors with functional electrical stimulation (FES). By automatically adjusting stimulation intensity based on real‐time muscle force signals, the system enhances wrist movement capability (14° to 47° elevation) and aids neural recovery through heightened ...
Zhiwei Hu   +9 more
wiley   +1 more source

SGCD: High‐Resolution Spatial Domain Characterization via Data Interpolation and Cell‐Type Deconvolution

open access: yesAdvanced Science, EarlyView.
SGCD presents a novel approach for tissue spatial domain identification by employing interpolation to estimate inter‐spot gene expression and deconvolution to resolve cell‐type composition in both sampled and interstitial regions. By integrating gene expression, cell type, and spatial coordinates within a graph contrastive learning framework, SGCD ...
Tianjiao Zhang   +7 more
wiley   +1 more source

Theory of random measurement errors: concepts, uses, and misuses. [PDF]

open access: yesArh Hig Rada Toksikol
Zauner B   +7 more
europepmc   +1 more source

MGPT: A Multi‐task Graph Prompt Learning Framework for Drug Discovery

open access: yesAdvanced Science, EarlyView.
MGPT is a unified multi‐task graph prompt learning model providing generalizable and robust graph representations for few‐shot drug association prediction. MGPT demonstrates the ability of seamless task switching and outperforms competitive approaches in few‐shot scenarios.
Yang Li   +4 more
wiley   +1 more source

Engineering Adenine Deaminase TadA for Precise and PAM‐Flexible Point Mutagenesis and Gradient‐Tuning Endogenous Protein Design

open access: yesAdvanced Science, EarlyView.
Base editing enables precise nucleotide substitutions but limited by bystander editing. This study engineers plant base editors by fusing optimized TadA variants with PAM‐flexible SpRY nickase, enabling A‐to‐G, C‐to‐T, and dual‐base conversions in a highly condensed window (≤3 nucleotides). Additionally, TadDBE (TadA Dual‐Base Editor)‐mediated directed
Kangli Sun   +14 more
wiley   +1 more source

Low‐Power Tunable Micro‐Plasma Device for Efficient and Scalable CO2 Valorization

open access: yesAdvanced Science, EarlyView.
Tunable in‐chip micro‐plasma generation leads to efficient, low‐power and scalable CO2 valorization under atmospheric pressure via vibrational excitation mechanism. Abstract Valorizing CO2 into chemical building blocks via efficient electrified processes could significantly decrease carbon emissions.
Bartu Karakurt   +5 more
wiley   +1 more source

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