Results 11 to 20 of about 640,924 (242)

A Conversation with Yuan Shih Chow

, 2006
Yuan Shih Chow was born in Hubei province in China, on September 1, 1924. The eldest child of a local militia and political leader, he grew up in war and turmoil.
Ying, Zhiliang, Zhang, Cun-Hui
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Signed group orthogonal designs and their applications

, 2015
Craigen introduced and studied {\it signed group Hadamard matrices} extensively in \cite{Craigenthesis, Craigen}. Livinskyi \cite{Ivan}, following Craigen's lead, studied and provided a better estimate for the asymptotic existence of signed group ...
Ghaderpour, Ebrahim
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Structures and waves in a nonlinear heat-conducting medium

, 2013
The paper is an overview of the main contributions of a Bulgarian team of researchers to the problem of finding the possible structures and waves in the open nonlinear heat conducting medium, described by a reaction-diffusion equation.
A.A. Samarskii, AA Samarskii, AA Samarskii, AA Samarskii, AS Kalashnikov, CJ Budd, CJ Budd, E Hairer, EP Zhidkov, ES Kurkina, GG Elenin, H Wilhelmsson, HA Levin, IG Barenblatt, IV Puzynin, K Eriksson, M Berger, M Dimova, MG Koleva, MI Bakirova, MK Gavurin, MM Adyutov, N Zmitrenko, S Dimova, S.N. Dimova, S.N. Dimova, SN Dimova, SN Dimova, SN Dimova, SN Dimova, SN Dimova, SN Dimova, SP Kurdyumov, SP Kurdyumov, TS Akhromeeva, VA Dorodnitsyn, VA Dorodnitsyn, VA Galaktionov, VA Galaktionov, VA Galaktionov, VA Galaktionov, VA Galaktionov, VA Galaktionov, VA Novikov   +43 more
core   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Four lectures on secant varieties

, 2013
This paper is based on the first author's lectures at the 2012 University of Regina Workshop "Connections Between Algebra and Geometry". Its aim is to provide an introduction to the theory of higher secant varieties and their applications.
A. Bernardi, A. Bernardi, A. Bernardi, A. Boralevi, A. Causa, A. Laface, A.J. Sommese, B. Sturmfels, C. Raicu, C.J. Hillar, D. Cartwright, D. Cartwright, D. Erman, D.J. Bates, D.Ž. Djoković, E. Allman, E. Allman, E. Arrondo, E. Ballico, E. Ballico, E. Ballico, E. Carlini, E. Carlini, E. Cattani, E. Postinghel, F. Enriques, F.S. Macaulay, G. Ballard, G. Boffi, G. Comas, G. Ni, G. Ottaviani, G. Ottaviani, H. Abo, H. Abo, H. Abo, H. Abo, H. Abo, H. Flenner, I.M. Gel’fand, I.M. Gel’fand, I.M. Gel’fand, J. Alexander, J. Alexander, J. Brachat, J. Buczyński, J. Chipalkatti, J. Sidman, J. Weyman, J.D. Hauenstein, J.M. Landsberg, J.M. Landsberg, J.M. Landsberg, J.M. Landsberg, J.M. Landsberg, J.M. Landsberg, J.M. Landsberg, J.M. Landsberg, K. Ranestad, L. Albera, L. Chiantini, L. Chiantini, L. Garcia, L. Lathauwer De, L. Lathauwer De, L. Lathauwer De, L. Lathauwer De, L. Lathauwer De, L. Oeding, L. Oeding, L. Oeding, L. Qi, M. Boij, M. Casanellas, M. Drton, M. Mella, M. Mella, M.A.A. Leeuwen van, M.C. Brambilla, M.C. Brambilla, M.V. Catalisano, M.V. Catalisano, M.V. Catalisano, M.V. Catalisano, M.V. Catalisano, P. Comon, P. Comon, P. Comon, P. Comon, P. Huggins, R. Fröberg, S. Abrescia, S. Friedland, S. Friedland, S. Friedland, S. Hu, T.G. Kolda, V. Silva de, V. Strassen, V.V. Williams, W. Buczyńska, È.B. Vinberg   +101 more
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The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source