Results 51 to 60 of about 53,121 (313)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Pengaruh Pendekatan Pembelajaran Realistic Mathematics Education Terhadap Pemahaman Konsep Matematika Siswa Kelas VII Di SMP Negeri 3 Tondano

, 2023
This research aims to improve students' understanding of mathematical concepts in Comparative material by using the Realistic Mathematics Education approach, in this case there is an increase in learning outcomes before being given treatment and after ...
Laurensia Mujono, Wulandari, Sulangi, Victor R., V. J. Runtu, Patricia   +2 more
core  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Development of a differentiated mathematics learning model based on students' learning style characteristics

Frontiers in Education
This study aimed to develop and evaluate a differentiated mathematics learning model based on students' learning style characteristics, namely visual, auditory, and kinesthetic, referred to as the DiMaLS Model. Employing a Research and Development (R&
Radiatul Adawiah, Nurdin Arsyad, Awi Dassa, Nurwati Djam’an   +3 more
doaj   +1 more source

Efforts To Improve The Mathematics Learning Outcomes Of Class VII Students At The Wusto Level By Applying The Snowball Thrawing Learning Model At The Imam An-Nasai Islamic Boarding School, Gowa Regency [PDF]

ITM Web of Conferences
This research is a classroom action research (CAR) conducted at PPTQ Imam An Nasai Gowa Regency which aims to improve mathematics learning outcomes using the snowball thrawing method.
Aisyah Nur, Anwar Azwan, Nurwakia, Nursyamsi, Suriani M., Jannah Miftahul, Hukma, Rezky Ramadhan Nur, Haeruddin   +8 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

The impact of online learning on the mathematics learning process in Indonesia: A meta-analysis

Journal of Technology and Science Education, 2023
The goal of this meta-analysis is to ascertain how online learning has affected Indonesian students' ability to learn mathematics. Descriptive analysis was used to compile info from 41 pieces of information about the research, such as sample size ...
Muhammad Turmuzi, Ulfa Lu'luilmaknun
doaj   +1 more source

A study on the identity of teacher educators: traits revealed by a Mathematics preceptor of the Pedagogical Residency Program

Revista Internacional de Pesquisa em Educação Matemática, 2023
This study presents partial results of the repercussions of the performance of a mathematics preceptor in the Pedagogical Residency Program (PRP). For this, we chose to use semi-structured interviews as an instrument of data production. After transcription, the analysis was performed in light of the characterization of the professional identity of the ...
Robson Alves Faria, Douglas da Silva Tinti   +1 more
openaire   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source