Results 111 to 120 of about 121,319 (360)

Mating type (MAT) locus and possible sexuality of the opportunistic pathogen Exophiala dermatitidis [PDF]

Fungal Genetics and Biology, 2019
Sexual reproduction among the black yeasts is generally limited to environmental saprobic species and is rarely observed among opportunists in humans. To date, a complete sexual cycle has not been observed in Exophiala dermatitidis. In this study, we aimed to gain insight into the reproductive mode of E.
Banu Metin, Aylin Döğen, Esra Yıldırım, G. Sybren de Hoog, Joseph Heitman, Macit Ilkit   +5 more
openaire   +5 more sources

20 questions on Adaptive Dynamics [PDF]

, 2005
Adaptive Dynamics is an approach to studying evolutionary change when fitness is density or frequency dependent. Modern papers identifying themselves as using this approach first appeared in the 1990s, and have greatly increased up to the present ...
Abrams, Abrams, Abrams, Altenberg, Arnold, Asmussen, Asmussen, Avise, Barton, Bolnick, Bulmer, Bulmer, Bürger, Bürger, Caisse, Christiansen, Christiansen, Cockerham, Crosby, Crow, Crow, D. WAXMAN, Dickinson, Dieckmann, Dieckmann, Diehl, Doebeli, Dooren, Dooren, Doorn, Doorn, Endler, Eshel, Eshel, Fear, Felsenstein, Fisher, Gavrilets, Gavrilets, Gavrilets, Gavrilets, Geritz, Geritz, Geritz, Ginzburg, Haldane, Hofbauer, Kimura, Kingman, Kisdi, Kostitzin, Lande, Lewontin, Ludwig, Marks, Matessi, Matessi, Matsuda, Maynard Smith, Metz, Metz, Mizera, Moore, Moore, Mylius, Nowak, Orr, Orr, Provine, Provine, Reed, Rice, Roughgarden, Roughgarden, S. GAVRILETS, Schaffer, Slatkin, Slatkin, Slatkin, Spencer, Spencer, Taylor, Tienderen, Turelli, Udovic, Vincent, Waxman, Welch, Wilson, Wright, Wright, Zeng   +91 more
core   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Epigenetic Chromatin Silencing: Bistability and Front Propagation

, 2007
The role of post-translational modification of histones in eukaryotic gene regulation is well recognized. Epigenetic silencing of genes via heritable chromatin modifications plays a major role in cell fate specification in higher organisms.
Alberts B, Allis C D, Anirvan M Sengupta, Arkin A, Bi X, Donze D, Fall C P, Gilbert S, Lodish H, Mohammad Sedighi, Ptashne M, Raser J M, Singer M S, Stillman B   +13 more
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

味噌醤油酵母Zygosaccharomyces酵母の接合遺伝子座(mating-type-like (MTL) loci)の多様性 [PDF]

, 2018
Variations of chromosomal structures and nucleotide sequences around mating-type-like (MTL) loci among Zygosaccharomyces species have been reported.
Ogata, Tomoo, オガタ, トモオ, 尾形, 智夫   +2 more
core  

Fungal genomes tell a story of ecological adaptations [PDF]

, 2014
One genome enables a fungus to have various lifestyles and strategies depending on environmental conditions and in the presence of specific counterparts.
Muszewska, Anna
core   +3 more sources

Analysis of the Structures of Mating-Type A and B Loci in Stropharia rugosoannulata Based on Genomic Data and Development of SNP Molecular Markers

Horticulturae
Stropharia rugosoannulata is a widely cultivated edible fungus with high economic and nutritional value. It is a tetrapolar heterothallic basidiomycete. The development of single nucleotide polymorphism (SNP) markers for mating-type identification holds ...
Panpan Zhang, Jiakun Shao, Xiao Li, Haodong Liu, Shangshang Xiao, Ao Ma, Ming Li, Jinghua Tian, Junling Wang, Peng Zhu, Yupu Shao, Shoumian Li, Guojie Li   +12 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source