Improving sequence-based genotype calls with linkage disequilibrium and pedigree information
, 2012 Whole and targeted sequencing of human genomes is a promising, increasingly feasible tool for discovering genetic contributions to risk of complex diseases.
Whittemore, Alice S., Zhou, Baiyu
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Low genetic variability, female-biased dispersal and high movement rates in an urban population of Eurasian badgersMeles meles [PDF]
, 2008 1. Urban and rural populations of animals can differ in their behaviour, both in order to meet their ecological requirements and due to the constraints imposed by different environments.
Bijlsma +66 more
core +2 more sources
Rapid and Efficient CRISPR/Cas9-Based Mating-Type Switching of Saccharomyces cerevisiae
G3: Genes, Genomes, Genetics, 2018 Rapid and highly efficient mating-type switching of Saccharomyces cerevisiae enables a wide variety of genetic manipulations, such as the construction of strains, for instance, isogenic haploid pairs of both mating-types, diploids and polyploids. We used
Ze-Xiong Xie +14 more
doaj +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Comparative Analysis of Mating Behavior Characteristics of Mutants at the white Locus of Drosophila melanogaster [PDF]
Учёные записки Казанского университета: Серия Естественные науки, 2017 Drosophila melanogaster serves as an excellent model system to study the control of innate behaviors. Behavior is the ability of animals to change their actions under the influence of internal and external factors, a characteristic feature of the animal ...
V.V. Kostenko
doaj
Memorias do Instituto Oswaldo Cruz, 2009 The opportunistic fungal pathogen Candida glabrata is the second most common isolate from bloodstream infections worldwide and is naturally less susceptible to the antifungal drug fluconazole than other Candida species. C.
María Teresa Lavaniegos-Sobrino +7 more
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Yeast mismatch repair components are required for stable inheritance of gene silencing.
PLoS Genetics, 2020 Alterations in epigenetic silencing have been associated with ageing and tumour formation. Although substantial efforts have been made towards understanding the mechanisms of gene silencing, novel regulators in this process remain to be identified.
Qian Liu +7 more
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Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Statistical methods for detecting genes associated with sperm competition in natural populations of Drosophila, using blocks of tightly linked single nucleotide polymorphisms : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Statistics at Massey University, Albany, New Zealand [PDF]
, 2007 The purpose of the project is to develop statistical methods for detecting genes associated with sperm competition in natural populations of Drosophila (fruit flies). The flies' genotype information given by Fiumera et al.
Werner, Lillian Li
core
The reintroduction of the Eurasian otter (Lutra lutra) into the Netherlands: hidden life revealed by noninvasive genetic monitoring [PDF]
, 2010 The last recorded presence of the Eurasian otter (Lutra lutra) in the Netherlands dates from 1989 and concerned a dead individual. In 2002 a reintroduction programme was started, and between June 2002 and April 2008 a total of 30 individuals (10 males ...
Boerwinkel, M.C. +7 more
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