Results 151 to 160 of about 746,215 (354)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Determinação do ácido quínico e derivados antioxidantes da erva mate (Ilex paraguariensis)

, 2022
Chornobai, Cesar Arthur Martins
openalex   +1 more source

The Effect of Mating System Differences on Nucleotide Diversity at the Phosphoglucose Isomerase Locus in the Plant Genus Leavenworthia [PDF]

, 1999
Fu-He Liu, Deborah Charlesworth, Martin Kreitman   +2 more
openalex   +1 more source

Genome-wide identification and expression analysis of MATE gene family in citrus fruit (Citrus clementina)

, 2022
Shengchao Liu, Yinchun Li, Heting Fang, Boyu Huang, Chenning Zhao, Chongde Sun, Shaojia Li, Kunsong Chen   +7 more
openalex   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Corrigendum: Chemical Ecology of Capnodis tenebrionis (L.) (Coleoptera: Buprestidae): Behavioral and Biochemical Strategies for Intraspecific and Host Interactions

Frontiers in Physiology, 2020
Giuseppe Bari, Andrea Scala, Vita Garzone, Rosanna Salvia, Cem Yalcin, Cem Yalcin, Pasqua Vernile, Antonella Maria Aresta, Osvaldo Facini, Rita Baraldi, Sabino A. Bufo, Heiko Vogel, Enrico de Lillo, Francesca Rapparini, Patrizia Falabella   +14 more
doaj   +1 more source

Highly Active Air Electrode with Enhanced Proton Conduction via Isovalent Doping in a Layered Perovskite for Reversible Protonic Ceramic Cells (Adv. Funct. Mater. 41/2025) [PDF]

Jiwon Yun, Hyeongsik Shin, Seungchan Kim, Boseok Seong, Seongjae Lee, Kyeounghak Kim, Sun Hee Choi, Sihyuk Choi   +7 more
openalex   +1 more source

Mating sequence, dominance and paternity success in captive male tammar wallabies [PDF]

, 2005
Emily Hynes, Carl D. Rudd, Peter Temple‐Smith, G. Sofronidis, Damien B.B.P. Paris, Geoff Shaw, Marilyn B. Renfree   +6 more
openalex   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source